Imidazo[4,5-b]pyridine, 5,7-dimethyl- (6CI,9CI)

Base Information

• Chemical Name: Imidazo[4,5-b]pyridine, 5,7-dimethyl- (6CI,9CI)
• CAS No.: 116599-55-4
• Molecular Formula: C₈H₉N₃
• Molecular Weight: 147.18
• Mol file: 116599-55-4.mol

Synonyms:Imidazo[4,5-b]pyridine,5,7-dimethyl- (6CI,9CI)

Chemical Property of Imidazo[4,5-b]pyridine, 5,7-dimethyl- (6CI,9CI)

Chemical Property:

• Boiling Point: 253.7±23.0 °C(Predicted)
• PKA: 8.74±0.40(Predicted)
• PSA: 41.57000
• Density: 1.26±0.1 g/cm3(Predicted)
• LogP: 1.57470

Purity/Quality:

97% ^*data from raw suppliers

5,7-Dimethyl-1H-imidazo[4,5-b]pyridine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Imidazo[4,5-b]pyridine, 5,7-dimethyl- (6CI,9CI)

There total 4 articles about Imidazo[4,5-b]pyridine, 5,7-dimethyl- (6CI,9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-bromo-5,7-dimethyl-1(3)H-imidazo[4,5-b]pyridine (92336-10-2) → 5,7-dimethyl-1(3)H-imidazo[4,5-b]pyridine (116599-55-4)

Guidance literature:

With sodium hydroxide; palladium on activated charcoal; platinum; Hydrogenation;

Reference yield:

2-amino-5-bromo-4,6-dimethylpyridine (89856-44-0) → 5,7-dimethyl-1(3)H-imidazo[4,5-b]pyridine (116599-55-4)

Guidance literature:

Multi-step reaction with 4 steps

1: concentrated H₂SO₄; concentrated aqueous HNO₃

2: SnCl₂; aqueous HCl

4: palladium/charcoal; platinum; aq. NaOH solution / Hydrogenation

With hydrogenchloride; sodium hydroxide; palladium on activated charcoal; sulfuric acid; nitric acid; platinum; tin(ll) chloride;

Reference yield:

2,3-diamino-4,6-dimethyl-5-bromo-pyridine (89728-15-4) → 5,7-dimethyl-1(3)H-imidazo[4,5-b]pyridine (116599-55-4)

Guidance literature:

Multi-step reaction with 2 steps

2: palladium/charcoal; platinum; aq. NaOH solution / Hydrogenation

With sodium hydroxide; palladium on activated charcoal; platinum;

upstream raw materials:

6-bromo-5,7-dimethyl-1⁽³⁾H-imidazo[4,5-b]pyridine

2-amino-5-bromo-4,6-dimethylpyridine

2,3-diamino-4,6-dimethyl-5-bromo-pyridine

2-amino-3-nitro-4,6-dimethyl-5-bromo-pyridine