89856-44-0

Basic information

• Product Name: 2-AMINO-5-BROMO-4 6-DIMETHYLPYRIDINE&
• Synonyms: 2-AMino-5-broMo-4,6-diMethylpyridine 97%;5-bromo-4,6-dimethyl-2-pyridinamine;6-Amino-2,4-dimethyl-3-bromopyridine;5-Bromo-4,6-dimethyl-2-pyridinamine, 6-Amino-3-bromo-2,4-lutidine;6-Amino-3-bromo-2,4-iutidine;3-Bromo-2,4-dimethylpyridin-6-amine;2-AMino-4,6-diMethyl-5-broMopyridine;5-BroMo-4,6-diMethylpyridin-2-aMine
• CAS NO: 89856-44-0
• Molecular Formula: C₇H₉BrN₂
• Molecular Weight: 201.06
• EINECS: 1312995-182-4
• Product Categories: Nucleotides;Amines;Aromatics;Bases & Related Reagents;Heterocycles
• Mol File: 89856-44-0.mol
• Article Data: 17

Chemical Properties

• Melting Point: 144-148 °C(lit.)
• Boiling Point: 257.689 °C at 760 mmHg
• Flash Point: 109.647 °C
• Appearance: /
• Density: 1.504
• Vapor Pressure: 0.014mmHg at 25°C
• Refractive Index: 1.603
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 5.46±0.48(Predicted)
• CAS DataBase Reference: 2-AMINO-5-BROMO-4 6-DIMETHYLPYRIDINE&(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5-BROMO-4 6-DIMETHYLPYRIDINE&(89856-44-0)
• EPA Substance Registry System: 2-AMINO-5-BROMO-4 6-DIMETHYLPYRIDINE&(89856-44-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-41-43
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 89856-44-0(Hazardous Substances Data)

Usage

Chemical Properties

White Powder

InChI:InChI=1/C7H9BrN2/c1-4-3-6(9)10-5(2)7(4)8/h3H,1-2H3,(H2,9,10)

Upstream product

• 99179-94-9 N-(5-bromo-4,6-dimethyl-[2]pyridyl)-acetamide 
• 5407-87-4 2-Amino-4,6-dimethylpyridine 
• 5407-88-5 N-(4,6-dimethyl-2-pyridinyl)acetamide 
• 128-08-5 N-Bromosuccinimide 

Downstream Products

• 627098-10-6 5-bromo-4,6-dimethyl-2-(dimethylamino)pyridine 
• 1330766-90-9 3-(benzyloxy)-6-(2,5-dimethyl-1H-pyrrol-1-yl)-2,4-dimethylpyridine 
• 1330766-91-0 2-(2,5-dimethyl-1H-pyrrol-1-yl)-5-benzyloxy-4-methyl-6-(10-benzyloxydecyl)-pyridine 
• 1330766-92-1 2-amino-5-benzyloxy-4-methyl-6-(10-benzyloxydecyl)-pyridine 
• 1330766-94-3 3-(benzyloxy)-6-(2,5-dimethyl-1H-pyrrol-1-yl)-2-[10-(methoxymethoxy)decyl]-4-methylpyridine 
• 1330766-95-4 6-amino-3-(benzyloxy)-2-[10-(methoxymethoxy)decyl]-4-methylpyridine 
• 1330766-97-6 3-(benzyloxy)-6-methoxy-2-(10-(methoxymethoxy)decyl)-4-methylpyridine 
• 1417621-00-1 (E)6-(3-(4-methoxybenzyloxy)propyl)-3-(dec-1-enyl)-2,4-dimethylpyridine 
• 89728-15-4 2,3-diamino-4,6-dimethyl-5-bromo-pyridine 
• 627098-09-3 6-methoxy-2,4-dimethylpyridin-3-ol 
• 819069-57-3 3-bromo-6-methoxy-2,4-dimethylpyridine 
• 89694-55-3 5-bromo-4,6-dimethyl-1,2-dihydropyridin-2-one 
• 89791-76-4 2-amino-3-nitro-4,6-dimethyl-5-bromo-pyridine 
• 89694-55-3 5-bromo-4,6-dimethylpyridin-2-ol 

Relevant articles and documents

Anibamine and Its Analogues: Potent Antiplasmodial Agents from Aniba citrifolia

In our continuing search for novel natural products with antiplasmodial activity, an extract of Aniba citrifolia was found to have good activity, with an IC50 value less than 1.25 μg/mL. After bioassay-directed fractionation, the known indolizinium alkaloid anibamine (1) and the new indolizinium alkaloid anibamine B (2) were isolated as the major bioactive constituents, with antiplasmodial IC50 values of 0.170 and 0.244 μM against the drug-resistant Dd2 strain of Plasmodium falciparum. The new coumarin anibomarin A (3), the new norneolignan anibignan A (5), and six known neolignans (7-12) were also obtained. The structures of all the isolated compounds were determined based on analyses of 1D and 2D NMR spectroscopic and mass spectrometric data, and the absolute configuration of anibignan A (5) was assigned from its ECD spectrum. Evaluation of a library of 28 anibamine analogues (13-40) indicated that quaternary charged analogues had IC50 values as low as 58 nM, while uncharged analogues were inactive or significantly less active. Assessment of the potential effects of anibamine and its analogues on the intraerythrocytic stages and morphological development of P. falciparum revealed substantial activity against ring stages for compounds with two C-10 side chains, while those with only one C-10 side chain exhibited substantial activity against trophozoite stages, suggesting different mechanisms of action.

PESTICIDAL COMPOUNDS

The present invention relates to the compounds of formula (I), and the N-oxides, stereoisomers, tautomers and agriculturally or veterinarily acceptable salts thereof wherein the variables are defined according to the description. The compounds of formula (I), as well as the N-oxides, stereoisomers, tautomers and agriculturally or veterinarily acceptable salts thereof, are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.

THERAPEUTIC INHIBITORY COMPOUNDS

The invention provides compounds of Formula I and Formula II: A-B-C-D-E-F-G-J (I) C-D-E-F-G-J (II) wherein A, B, C, D, E, F, G, and J have any of the values defined in the specification, and salts thereof. The compounds are useful for inhibiting plasma kallikrein, and for treating a disease or condition in an animal where inhibition of plasma kallikrein is indicated.