1,1,2,2-Tetramethoxycyclohexane

Base Information

• Chemical Name: 1,1,2,2-Tetramethoxycyclohexane
• CAS No.: 163125-34-6
• Molecular Formula: C10H20O4
• Molecular Weight: 204.266
• DSSTox Substance ID: DTXSID30369910
• Nikkaji Number: J826.477E
• Wikidata: Q82157189
• Mol file: 163125-34-6.mol

Synonyms:1,1,2,2-tetramethoxycyclohexane;163125-34-6;Cyclohexane, 1,1,2,2-tetramethoxy-;Cyclohexane,1,1,2,2-tetramethoxy-;SCHEMBL3248407;DTXSID30369910;AKOS000276704;CS-0336946;InChI=1/C10H20O4/c1-11-9(12-2)7-5-6-8-10(9,13-3)14-4/h5-8H2,1-4H

Chemical Property of 1,1,2,2-Tetramethoxycyclohexane

Chemical Property:

• Appearance/Colour: Clear yellow to brown-yellow liquid
• Vapor Pressure: 0.138mmHg at 25°C
• Refractive Index: 1.454-1.46
• Boiling Point: 224.2 °C at 760 mmHg
• Flash Point: 70.1 °C
• PSA: 36.92000
• Density: 1.01 g/cm³
• LogP: 1.53860
• Storage Temp.: 0-6°C
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 204.13615911
• Heavy Atom Count: 14
• Complexity: 153

Purity/Quality:

99% ^*data from raw suppliers

1,1,2,2-Tetramethoxycyclohexane 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1(CCCCC1(OC)OC)OC

Technology Process of 1,1,2,2-Tetramethoxycyclohexane

There total 2 articles about 1,1,2,2-Tetramethoxycyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

methanol (67-56-1) + cyclohexane-1,2-dione (765-87-7) → 1,1,2,2-tetramethoxycyclohexane (163125-34-6)

Guidance literature:

With sulfuric acid; trimethyl orthoformate; for 5h; Heating;

DOI:10.3987/com-99-8724

Reference yield: 75.0%

cyclohexane-1,2-dione (765-87-7) + trimethyl orthoformate (149-73-5) → 1,1,2,2-tetramethoxycyclohexane (163125-34-6)

Guidance literature:

With sulfuric acid; In methanol; for 16h; Heating;

Reference yield: 61.0%

1,1,2,2-tetramethoxycyclohexane (163125-34-6) + benzyl L-rhamnopyranoside (251361-11-2) → benzyl 2,3-O-(1',2'-dimethoxycyclohexane-1',2'-diyl)-α-L-rhamnopyranoside + benzyl 3,4-O-(1',2'-dimethoxycyclohexane-1',2'-diyl)-α-L-rhamnopyranoside (202717-74-6)

Guidance literature:

With camphor-10-sulfonic acid; In methanol; for 1.25h; Heating;

DOI:10.1021/jo971846x

upstream raw materials:

cyclohexane-1,2-dione

trimethyl orthoformate

methanol

Downstream raw materials:

(1'S,2'S)-Phenyl 3,4-O-(1',2'-dimethoxycyclohexane-1',2'-diyl)-1-seleno-α-D-mannopyranoside

(1'R,2'R)-Methyl 3,4-O-(1',2'-dimethoxycyclohexane-1',2'-diyl)-α-L-rhamnopyranoside

benzyl 3,4-O-(1',2'-dimethoxycyclohexane-1',2'-diyl)-α-L-rhamnopyranoside

4,5-O-(1',2'-dimethoxycyclohexane-1',2'-diyl)-3-O-methyl-D-chiro-inositol