1-Acetylpyrrolidine-2-carbaldehyde

Base Information

Chemical Name:1-Acetylpyrrolidine-2-carbaldehyde
CAS No.:115859-55-7
Molecular Formula:C₇H₁₁NO₂
Molecular Weight:141.17
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30555558
Nikkaji Number:J515.826E
Mol file:115859-55-7.mol

Synonyms:1-acetylpyrrolidine-2-carbaldehyde;115859-55-7;1-Acetyl-pyrrolidine-2-carbaldehyde;2-Pyrrolidinecarboxaldehyde, 1-acetyl- (9CI);SCHEMBL4041080;DTXSID30555558;MFCD11583079;AKOS006316010;2-Pyrrolidinecarboxaldehyde, 1-acetyl-;AM90769;SB46189;BS-50411;E76333;EN300-359853;A893795

Suppliers and Price of 1-Acetylpyrrolidine-2-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-Acetylpyrrolidine-2-carbaldehyde 95+%
1g
$ 541.00

Chemenu
1-Acetylpyrrolidine-2-carbaldehyde 95%
1g
$ 506.00

Alichem
1-Acetylpyrrolidine-2-carbaldehyde
1g
$ 437.00

Total 11 raw suppliers

Chemical Property of 1-Acetylpyrrolidine-2-carbaldehyde

Chemical Property:

PSA：37.38000
LogP:0.13410
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:-0.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:141.078978594
Heavy Atom Count:10
Complexity:156

Purity/Quality:

97% ^*data from raw suppliers

1-Acetylpyrrolidine-2-carbaldehyde 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N1CCCC1C=O

Technology Process of 1-Acetylpyrrolidine-2-carbaldehyde

There total 11 articles about 1-Acetylpyrrolidine-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.5%

: 66158-68-7,123958-87-2
(S)-1-(2-(hydroxymethyl) pyrrolidin-1-yl)ethanone

: 73323-64-5,115859-55-7
(S)-1-acetylpyrrolidine-2-carbaldehyde

Guidance literature:: (S)-1-(2-(hydroxymethyl) pyrrolidin-1-yl)ethanone; With oxalyl dichloride; In dichloromethane; at -78 ℃; for 0.5h; Inert atmosphere;

With triethylamine; In dichloromethane; Inert atmosphere;

Reference yield: 74.4%

: 66158-68-7,123958-87-2
(R)-1-(2-(hydroxymethyl)pyrrolidin-1-yl)ethan-1-one

: 67-68-5,8070-53-9
dimethyl sulfoxide

: 852324-30-2,115859-55-7
(R)-1-acetylpyrrolidine-2-carbaldehyde

Guidance literature:: With oxalyl dichloride; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

Reference yield:

: 692-33-1
N-allylacetamide

: 201230-82-2
carbon monoxide

: 4030-18-6
N-(acetyl)pyrrolidine

: 24431-53-6
2-methyl-3-(acetylamino)propanal

: 73323-64-5,115859-55-7
1-acetyl-2-formylpyrrolidine

Guidance literature:: With RhCl(PPh₃)3; In tetrahydrofuran; at 80 ℃; for 18h; under 62057.8 Torr; Yield given. Yields of byproduct given;
DOI:10.1021/jo00253a051