5,11,17,23-TETRAKIS-DIMETHYLAMINOMETHYLCALIX[4!ARENE

Base Information

• Chemical Name: 5,11,17,23-TETRAKIS-DIMETHYLAMINOMETHYLCALIX[4!ARENE
• CAS No.: 115421-52-8
• Molecular Formula: C40H52 N4 O4
• Molecular Weight: 652.89
• Mol file: 115421-52-8.mol

Synonyms:5,11,17,23-tetra(tert-butyl)-25,27-dimethoxy-26,28-dihydroxycalix[4]arene;p-tetrakis[(N,N-dimethylamino)methyl]-25,26,27,28-tetrahydroxycalix[4]arene;5,11,17,23-tetrakis[(dimethylamino)methyl]-25,26,27,28-tetrahydroxycalix[4]arene;5,11,17,23-tetramethoxy-25,26,27,28-tetrakis(chloromethyl)calix[4]arene;5,11,17,23-tetra-tert-butyl-25,27-dihydroxy-26,28-dimethoxycalix[4]arene;5,11,17,23-tetrakis(1,1-dimethylethyl)-25,27-dihydroxy-26,28-dimethoxycalix[4]arene;cationic calix [4]arene;tetramethoxy-p-tetrachloromethylcalix<4>arene;5,11,17,23-Tetrakis<(dimethylamino)methyl>calix<4>arene-25,26,27,28-tetrol;5,11,17,23-tetra-tert-butyl-25,27-dihydroxy-26,28-di(methyloxy)calix[4]arene;1,3-Dimethoxy-4-tert-butylcalix[4]arene;5,11,17,23-tetrachloromethyl-25,26,27,28-tetramethoxycalix [4] arene;5,11,17,23-tetrakis[(dimethylamino)methyl]pentacyclo[19.3.1.1(3,7).1(9,13).1(15,19)]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-25,26,27,28-tetrol;5,11,17,23-tetra-tert-butyl-25,27-dihydroxy-26,28-bis(methyloxy)calix[4]arenetitanium(IV) dichloride;5,11,17,23-tetrakis(chloromethyl)-25,26,27,28-tetramethoxycalix[4]arene;24,26-dimethoxy-25,27-dihydroxy-5,11,17,23-tetra(4-tert-butyl)calix[4]arene;

Chemical Property of 5,11,17,23-TETRAKIS-DIMETHYLAMINOMETHYLCALIX[4!ARENE

Chemical Property:

• Melting Point: 158-162°C
• Boiling Point: 710.1±60.0 °C(Predicted)
• PKA: 9.22±0.20(Predicted)
• PSA: 12.96000
• Density: 1.182±0.06 g/cm3(Predicted)
• LogP: 6.77400

Purity/Quality:

98%min ^*data from raw suppliers

5,11,17,23-TETRAKIS-DIMETHYLAMINOMETHYLCALIX[4]ARENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,11,17,23-TETRAKIS-DIMETHYLAMINOMETHYLCALIX[4!ARENE

There total 4 articles about 5,11,17,23-TETRAKIS-DIMETHYLAMINOMETHYLCALIX[4!ARENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 25,26,27,28-tetrakis(hydroxy)calix[4]arene (248590-47-8,74568-07-3) + dimethyl amine (124-40-3) → 5,11,17,23-tetrakis[(dimethylamino)methyl]pentacyclo[19.3.1.1(3,7).1(9,13).1(15,19)]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-25,26,27,28-tetrol (115421-52-8)

Guidance literature:

In tetrahydrofuran; water; acetic acid; for 24h; Ambient temperature;

DOI:10.1021/ja00226a034

Reference yield:

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene (157432-87-6,288302-11-4,288302-12-5,60705-62-6) → 5,11,17,23-tetrakis[(dimethylamino)methyl]pentacyclo[19.3.1.1(3,7).1(9,13).1(15,19)]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-25,26,27,28-tetrol (115421-52-8)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃ / toluene

2: 69 percent / acid

With aluminium trichloride; acid; In toluene;

DOI:10.1016/S0040-4039(00)92026-4

Reference yield:

phenol (108-95-2,27073-41-2) → 5,11,17,23-tetrakis[(dimethylamino)methyl]pentacyclo[19.3.1.1(3,7).1(9,13).1(15,19)]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-25,26,27,28-tetrol (115421-52-8)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃ / toluene

2: 69 percent / acid

With aluminium trichloride; acid; In toluene;

DOI:10.1016/S0040-4039(00)92026-4

upstream raw materials:

formaldehyd

25,26,27,28-tetrakis(hydroxy)calix[4]arene

dimethyl amine

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene

Downstream raw materials:

5,11,17,23-tetrakis(cyanomethyl)-25,26,27,28-tetrakis<(p-tolylsulfonyl)oxy>calix<4>arene

5,11,17,23-tetrakis(cyanomethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene

5,11,17,23-Tetrakis<(propargyloxy)methyl>-25,26,27,28-tetrakis(benzyloxy)calix<4>arene

5,11,17,23-Tetrakis<(benzyloxy)methyl>-25,26,27,28-tetrahydroxycalix<4>arene