2,6-dinitro-4-fluoroanisole

Base Information

• Chemical Name: 2,6-dinitro-4-fluoroanisole
• CAS No.: 342-49-4
• Molecular Formula: C₇H₅FN₂O₅
• Molecular Weight: 216.126
• Mol file: 342-49-4.mol

Synonyms:2,6-dinitro-4-fluoroanisole

Chemical Property of 2,6-dinitro-4-fluoroanisole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-dinitro-4-fluoroanisole

There total 9 articles about 2,6-dinitro-4-fluoroanisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

1-fluoro-4-methoxybenzene (459-60-9) → 2,6-dinitro-4-fluoroanisole (342-49-4)

Guidance literature:

With sulfuric acid; nitric acid; at 0 - 20 ℃; for 1h;

DOI:10.1002/ejoc.201600657

Reference yield:

4-fluoro-2,6-dinitrophenol (364-32-9) + dimethyl sulfate (77-78-1) → 2,6-dinitro-4-fluoroanisole (342-49-4)

Guidance literature:

With potassium carbonate; In acetone; at 60 ℃; for 20h;

Reference yield:

1-fluoro-4-methoxybenzene (459-60-9) → 2,6-dinitro-4-fluoroanisole (342-49-4) + 4-fluoro-1-methoxy-2-nitrobenzene (445-83-0) + 4-fluoro-2-(trinitromethyl)anisole (110175-19-4)

Guidance literature:

With tetranitromethane; In dichloromethane; at 25 ℃; for 16h; Title compound not separated from byproducts; Irradiation;

DOI:10.1021/ja00259a035

upstream raw materials:

1-fluoro-4-methoxybenzene

tetranitromethane

sulfuric acid

nitric acid

Downstream raw materials:

4-Fluoro-2,6-dinitroaniline

N-methyl-4-fluoro-2,6-dinitroaniline

C₇H₉FN₂O

4-fluoro-2,6-dinitro-phenol; potassium-compound