5-[(Dimethylamino)sulfonyl]-2-thiophenecarboxylic acid

Base Information

Chemical Name:5-[(Dimethylamino)sulfonyl]-2-thiophenecarboxylic acid
CAS No.:7311-36-6
Molecular Formula:C₇H₉NO₄S₂
Molecular Weight:235.285
Hs Code.:
DSSTox Substance ID:DTXSID101211126

Synonyms:7311-36-6;5-[(Dimethylamino)sulfonyl]-2-thiophenecarboxylic acid;SCHEMBL7895808;DTXSID101211126

Suppliers and Price of 5-[(Dimethylamino)sulfonyl]-2-thiophenecarboxylic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-[(Dimethylamino)sulfonyl]-2-thiophenecarboxylic acid

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:234.99730012
Heavy Atom Count:14
Complexity:319

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)S(=O)(=O)C1=CC=C(S1)C(=O)O

Technology Process of 5-[(Dimethylamino)sulfonyl]-2-thiophenecarboxylic acid

There total 5 articles about 5-[(Dimethylamino)sulfonyl]-2-thiophenecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41895-10-7
N,N-dimethylthiophene-2-sulfonamide

dry ice) tetrahydrofuran: dry ice) tetrahydrofuran

: 7311-36-6
5-(dimethylsulfamoyl)thiophene-2-carboxylic acid

: 4111-54-0
lithium diisopropyl amide

Guidance literature:: With sodium hydroxide; n-butyllithium; diisopropylamine; In tetrahydrofuran; 2-thiophenylcarboxylic acid; diethyl ether;

Reference yield:

: ethyl 5-(dimethylsulfamoyl)thiophene-2-carboxylate

: 7311-36-6
5-(dimethylsulfamoyl)thiophene-2-carboxylic acid

Guidance literature:: With lithium hydroxide monohydrate; water; In tetrahydrofuran; at 20 ℃; for 1h;

Reference yield:

: 527-72-0
2-thiophenylcarboxylic acid

: 124-40-3
dimethyl amine

: 7311-36-6
5-(dimethylsulfamoyl)thiophene-2-carboxylic acid

: 4-(dimethylsulfamoyl)thiophene-2-carboxylic acid

Guidance literature:: 2-thiophenylcarboxylic acid; With chlorosulfonic acid; at 100 ℃; for 1h;

dimethyl amine; In tetrahydrofuran; at 25 ℃; for 2h;