4-[Bis(4-Fluorophenyl)methylene]piperidine hydrobromide

Base Information

Chemical Name:4-[Bis(4-Fluorophenyl)methylene]piperidine hydrobromide
CAS No.:111627-29-3
Molecular Formula:C18H17 F2 N . Br H
Molecular Weight:366.26
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70598080
Mol file:111627-29-3.mol

Synonyms:111627-29-3;4-[Bis(4-Fluorophenyl)methylene]piperidine hydrobromide;4-[BIS(4-FLUOROPHENYL)METHYLENE]PIPERIDINEHYDROBROMIDE;4-[Bis(4-Fluorophenyl)methylene]-piperidine hydrobromide;4-[bis(4-fluorophenyl)methylidene]piperidine;hydrobromide;QYGTZLORLCADEX-UHFFFAOYSA-N;SCHEMBL7444095;DTXSID70598080;MFCD02093809;MB02229;F73089;4-[Bis(4-Fluorophenyl)Methylene]Piperidine Hydrobromide (1:1);4-[BIS(4-FLUOROPHENYL)METHYLIDENE]PIPERIDINE HYDROBROMIDE;4-[Bis(4-fluorophenyl)methylidene]piperidine--hydrogen bromide (1/1)

Suppliers and Price of 4-[Bis(4-Fluorophenyl)methylene]piperidine hydrobromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-[Bis(4-Fluorophenyl)methylene]-piperidine hydrobromide 95+%
1g
$ 1647.00

Matrix Scientific
4-[Bis(4-Fluorophenyl)methylene]-piperidine hydrobromide 95+%
250mg
$ 738.00

Crysdot
4-[Bis(4-Fluorophenyl)methylene]piperidinehydrobromide 95+%
1g
$ 772.00

Chemenu
4-[Bis(4-Fluorophenyl)methylene]-piperidinehydrobromide 95%
1g
$ 729.00

American Custom Chemicals Corporation
4-(BIS(4-FLUOROPHENYL)METHYLENE)PIPERIDINEHYDROBROMIDE 95.00%
5G
$ 3811.50

Alichem
4-[Bis(4-Fluorophenyl)methylene]piperidinehydrobromide
1g
$ 640.56

AK Scientific
4-[Bis(4-Fluorophenyl)methylene]piperidinehydrobromide
250mg
$ 1046.00

Total 10 raw suppliers

Chemical Property of 4-[Bis(4-Fluorophenyl)methylene]piperidine hydrobromide

Chemical Property:

Vapor Pressure:3.99E-08mmHg at 25°C
Boiling Point:435.9°C at 760 mmHg
Flash Point:217.4°C
PSA：12.03000
LogP:5.43700
Storage Temp.:Inert atmosphere,Room Temperature
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:365.05907
Heavy Atom Count:22
Complexity:331

Purity/Quality:

98%min ^*data from raw suppliers

4-[Bis(4-Fluorophenyl)methylene]-piperidine hydrobromide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1=C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F.Br

Technology Process of 4-[Bis(4-Fluorophenyl)methylene]piperidine hydrobromide

There total 4 articles about 4-[Bis(4-Fluorophenyl)methylene]piperidine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 111627-27-1
α,α-bis(4-fluorophenyl)-1-(phenylsulfonyl)-4-piperidinemethanol

: 108-95-2,27073-41-2
phenol

: 111627-29-3
4-[bis(4-fluorophenyl)methylene]-piperidine monohydrobromide

Guidance literature:: In hydrogen bromide;

Reference yield:

: 1126-09-6
4-carbethoxypiperidine

: 111627-29-3
4-[bis(4-fluorophenyl)methylene]-piperidine monohydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / pyridine / 2 h / Ambient temperature

2: diethyl ether; tetrahydrofuran / 12 h / Ambient temperature

3: phenol, 48percent aq. HBr / 7 h / Heating

With pyridine; hydrogen bromide; phenol; In tetrahydrofuran; diethyl ether;
DOI:10.1021/jm00114a009

Reference yield:

: 111627-26-0
1-(phenylsulfonyl)-4-piperidinecarboxylic acid ethyl ester

: 111627-29-3
4-[bis(4-fluorophenyl)methylene]-piperidine monohydrobromide

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether; tetrahydrofuran / 12 h / Ambient temperature

2: phenol, 48percent aq. HBr / 7 h / Heating

With hydrogen bromide; phenol; In tetrahydrofuran; diethyl ether;
DOI:10.1021/jm00114a009