1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE

Base Information

• Chemical Name: 1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE
• CAS No.: 109384-27-2
• Molecular Formula: C5H10 N2 O . Cl H
• Molecular Weight: 150.608
• Hs Code.: 2933599090
• Mol file: 109384-27-2.mol

Synonyms:Piperazinone,1-methyl-, monohydrochloride (9CI); 1-Methylpiperazin-2-one hydrochloride

Chemical Property of 1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE

Chemical Property:

• PSA: 32.34000
• LogP: 0.11670
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Methylpiperazin-2-oneHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE

There total 2 articles about 1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-tert-butoxycarbonyl-4-methyl-3-oxopiperazine (109384-26-1) → 1-methylpiperazin-2-one hydrochloride (109384-27-2,1185292-91-4)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 1h;

Reference yield:

→ 1-methylpiperazin-2-one hydrochloride (109384-27-2,1185292-91-4)

Guidance literature:

Reference yield: 100.0%

1-methylpiperazin-2-one hydrochloride (109384-27-2,1185292-91-4) → 4-methyl-3-oxopiperazin-1-ium monotrifluoroacetate (194350-88-4)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1.5h;

upstream raw materials:

1-tert-butoxycarbonyl-4-methyl-3-oxopiperazine

Downstream raw materials:

4-methyl-3-oxopiperazin-1-ium monotrifluoroacetate

1-methylpiperazin-2-one

4-{3-[4-amino-5-(2-phenyl-chroman-7-yl)-pyrrolo[2,3-d]pyrimidin-7-yl]-cyclobutylmethyl}-1-methyl-piperazin-2-one

(R)-quinuclidin-3-yl 2-(4-methyl-3-oxopiperazin-1-yl)-2-phenylacetate

Refernces

• 1、 -. "PYRAZOLE DERIVATIVE". Page/Page column 43-44. . Retrieved 2010/11/27.
• 2、 -. "FIVE-MEMBERED HETEROCYCLIC DERIVATIVE". Page/Page column 47. . Retrieved 2010/11/08.