acide 5-(tricyclo<3.3.1.1^3,7>dec-1-yl)-tetrahydro-2-oxo-5-phenylfurane-3-carboxylique

Base Information

• Chemical Name: acide 5-(tricyclo<3.3.1.1^3,7>dec-1-yl)-tetrahydro-2-oxo-5-phenylfurane-3-carboxylique
• CAS No.: 134753-57-4
• Molecular Formula: C₂₁H₂₄O₄
• Molecular Weight: 340.419
• Mol file: 134753-57-4.mol

Synonyms:acide 5-(tricyclo<3.3.1.1^3,7>dec-1-yl)-tetrahydro-2-oxo-5-phenylfurane-3-carboxylique

Chemical Property of acide 5-(tricyclo<3.3.1.1^3,7>dec-1-yl)-tetrahydro-2-oxo-5-phenylfurane-3-carboxylique

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of acide 5-(tricyclo<3.3.1.1^3,7>dec-1-yl)-tetrahydro-2-oxo-5-phenylfurane-3-carboxylique

There total 1 articles about acide 5-(tricyclo<3.3.1.1^3,7>dec-1-yl)-tetrahydro-2-oxo-5-phenylfurane-3-carboxylique which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

5-(tricyclo<3.3.1.13,7>dec-1-yl)-dihydro-5-phenylfuran-2(3H)-one (134753-56-3) + magnesium methyl carbonate (4861-79-4) → acide 5-(tricyclo<3.3.1.13,7>dec-1-yl)-tetrahydro-2-oxo-5-phenylfurane-3-carboxylique (134753-57-4)

Guidance literature:

In N,N-dimethyl-formamide; Heating;

DOI:10.1016/0223-5234(91)90213-7

Reference yield: 56.0%

acide 5-(tricyclo<3.3.1.13,7>dec-1-yl)-tetrahydro-2-oxo-5-phenylfurane-3-carboxylique (134753-57-4) → 5-(tricyclo<3.3.1.13,7>dec-1-yl)-dihydro-3-methylene-5-phenylfuran-2(3H)-one (97839-58-2) + 5-(tricyclo<3.3.1.13,7>dec-1-yl)-dihydro-3-(dimethylaminomethyl)-5-phenylfuran-2(3H)-one (777821-90-6)

Guidance literature:

With formaldehyd; dimethyl amine; In ethanol; at 0 ℃; for 30h;

DOI:10.1016/0223-5234(91)90213-7

Reference yield: 56.0%

acide 5-(tricyclo<3.3.1.13,7>dec-1-yl)-tetrahydro-2-oxo-5-phenylfurane-3-carboxylique (134753-57-4) + dimethyl amine (124-40-3) → 5-(tricyclo<3.3.1.13,7>dec-1-yl)-dihydro-3-methylene-5-phenylfuran-2(3H)-one (97839-58-2) + 5-(tricyclo<3.3.1.13,7>dec-1-yl)-dihydro-3-(dimethylaminomethyl)-5-phenylfuran-2(3H)-one (777821-90-6)

Guidance literature:

With formaldehyd; In ethanol; at 0 ℃; for 30h;

DOI:10.1016/0223-5234(91)90213-7

upstream raw materials:

5-(tricyclo<3.3.1.1^3,7>dec-1-yl)-dihydro-5-phenylfuran-2(3H)-one

magnesium methyl carbonate

Downstream raw materials:

5-(tricyclo<3.3.1.1^3,7>dec-1-yl)-dihydro-3-methylene-5-phenylfuran-2(3H)-one

5-(tricyclo<3.3.1.1^3,7>dec-1-yl)-dihydro-3-(dimethylaminomethyl)-5-phenylfuran-2(3H)-one

1-(tricyclo<3.3.1.1^3,7>dec-1-yl)-3-(dimethylaminomethyl)-1-phenylbutane-1,4-diol