Chlorodiethylisopropylsilane

Base Information

• Chemical Name: Chlorodiethylisopropylsilane
• CAS No.: 107149-56-4
• Molecular Formula: C7H17 Cl Si
• Molecular Weight: 164.75
• European Community (EC) Number: 620-829-7
• DSSTox Substance ID: DTXSID90403667
• Nikkaji Number: J534.066G
• Wikidata: Q82207395
• Mol file: 107149-56-4.mol

Synonyms:Chlorodiethylisopropylsilane;107149-56-4;Diethylisopropylsilyl Chloride;chloro-diethyl-propan-2-ylsilane;Diethylisopropylsilylchloride;chlorodiethyl(propan-2-yl)silane;Silane, chlorodiethyl(1-methylethyl)-;Diethylisopropylchlorosilane;chlorodiethyl(isopropyl)silane;SCHEMBL1194883;DTXSID90403667;Chlorodiethylisopropylsilane, 98%;OSBPGFIPLLCQMO-UHFFFAOYSA-N;MFCD00191631;AKOS015848625;SB66529;BS-44079;D2262;FT-0693140;EN300-359701;T70057;J-001719

Chemical Property of Chlorodiethylisopropylsilane

Chemical Property:

• Vapor Pressure: 3.4mmHg at 25°C
• Refractive Index: n20/D 1.438(lit.)
• Boiling Point: 73 °C32 mm Hg(lit.)
• Flash Point: 100 °F
• PSA: 0.00000
• Density: 0.892 g/mL at 25 °C(lit.)
• LogP: 3.62050
• Storage Temp.: Refrigerator
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 164.0788048
• Heavy Atom Count: 9
• Complexity: 77

Purity/Quality:

98%,99%, ^*data from raw suppliers

Chlorodiethylisopropylsilane ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 10-14-34
• Safety Statements: 16-26-36/37/39-43-45-7/8

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC[Si](CC)(C(C)C)Cl

Technology Process of Chlorodiethylisopropylsilane

There total 3 articles about Chlorodiethylisopropylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

isopropyl chloride (75-29-6) + diethyldichlorosilane (1719-53-5) → chlorodiethylisopropylsilane (107149-56-4)

Guidance literature:

With lithium; In Petroleum ether; at 50 ℃; for 1h;

DOI:10.1246/bcsj.61.2369

Reference yield:

1,1,1-trichloro-2-methyl-1-silapropane (4170-46-1) + ethyllithium (811-49-4) → chlorodiethylisopropylsilane (107149-56-4)

Guidance literature:

In tetrahydrofuran; diethyl ether; for 18h; Ambient temperature;

DOI:10.1021/jm00387a011

Reference yield:

isopropyllithium (1888-75-1) + diethyldichlorosilane (1719-53-5) → chlorodiethylisopropylsilane (107149-56-4)

Guidance literature:

DOI:10.1016/S0040-4039(00)85053-4

upstream raw materials:

1,1,1-trichloro-2-methyl-1-silapropane

ethyllithium

isopropyl chloride

diethyldichlorosilane

Downstream raw materials:

diethyl(isopropyl)silyl trifluoromethanesulfonate

(2S,4R,5R,6E)-2-benzoyloxy-5-diethylisopropylsilyloxy-4-methyloct-6-en-3-one

phenyl 2-amino-2-deoxy-3,4-di-O-diethylisopropylsilyl-1-thio-α-D-xylopyranoside

phenyl 2-deoxy-3,4-di-O-diethylisopropylsilyl-2-N-methyl-N-trichloroethoxycarbamoyl-1-thio-α-D-xylopyranoside

Refernces

• 1、 Peters, Richard H.,Crowe, David F.,Tanabe, Masato,Avery, Mitchell A.,Chong, Wesley K. M.. "Steroidal Silicon Side-Chain Analogues as Potential Antifertility Agents". . p. 646 - 652. Retrieved 2007/10/02.