4-Hydrazinylpyridin-2(1H)-one

Base Information

• Chemical Name: 4-Hydrazinylpyridin-2(1H)-one
• CAS No.: 106689-41-2
• Molecular Formula: C5H7 N3 O
• Molecular Weight: 125.13
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID30544967
• Wikidata: Q82422294
• Mol file: 106689-41-2.mol

Synonyms:4-Hydrazinylpyridin-2(1H)-one;106689-41-2;4-hydrazinyl-1H-pyridin-2-one;4-hydrazino-1H-pyridin-2-one;4-HYDRAZINYLPYRIDIN-2-OL;MFCD18071580;4-HYDRAZINYL-2(1H)-PYRIDINONE;4-hydrazinopyrid-2-one;2(1H)Pyridinone,4hydrazino;SCHEMBL402331;DTXSID30544967;ICQHVQJVRZINSO-UHFFFAOYSA-N;BCP14942;AKOS006336937;DS-5041;SB52906;SY119822;CS-0036081;W16830;EN300-2485133

Chemical Property of 4-Hydrazinylpyridin-2(1H)-one

Chemical Property:

• PSA: 71.17000
• LogP: 0.84610
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• XLogP3: -0.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 125.058911855
• Heavy Atom Count: 9
• Complexity: 183

Purity/Quality:

97% ^*data from raw suppliers

4-Hydrazinylpyridin-2(1H)-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CNC(=O)C=C1NN

Technology Process of 4-Hydrazinylpyridin-2(1H)-one

There total 2 articles about 4-Hydrazinylpyridin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.3%

3-deazauracil (626-03-9,84719-31-3) → 4-hydrazinylpyridin-2(1H)-one (106689-41-2)

Guidance literature:

With 2-methoxy-ethanol; hydrazine hydrate; In water; at 20 ℃; for 24h;

Reference yield: 83.0%

4-hydroxy-2-pyridone (626-03-9) → 4-hydrazinylpyridin-2(1H)-one (106689-41-2)

Guidance literature:

With hydrazine hydrate; In 2-methoxy-ethanol; for 24h; Heating;

DOI:10.1016/S0040-4020(01)90610-6

Reference yield: 80.5%

4-methoxycyclohexanone (13482-23-0) + 4-hydrazinylpyridin-2(1H)-one (106689-41-2) → N-(4-methoxycyclohexylidene)-N'-(1H-pyrid-2-on-4-yl)hydrazine (111380-48-4)

Guidance literature:

In ethanol; Heating;

DOI:10.1021/jm00397a023

upstream raw materials:

4-hydroxy-2-pyridone

3-deazauracil

Downstream raw materials:

N-(4-methoxycyclohexylidene)-N'-(1H-pyrid-2-on-4-yl)hydrazine

N-(4-methylcyclohexylidene)-N'-(1H-pyrid-2-one)hydrazine

1-(3-Dimethylamino-propylamino)-5-methyl-5H-pyrido[4,3-b]indol-8-ol

4-(5-sec-butyl-3-(4-fluorophenyl)-1H-pyrazol-1-yl)pyridine-2(1H)-one

Refernces

• 1、 -. "PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF". Page/Page column 11. . Retrieved 2008/06/13.
• 2、 Hung, Nguyen Chi,Bisagni, Emile. "AUTRE VOIE D'ACCES AUX 5H-PYRIDOPYRROLOPYRIDINES ET LEUR TRANSFORMATION EN DERIVES N-5 ET N-8 SUBSTITUES". . p. 2303 - 2310. Retrieved 2007/10/02.