111380-48-4

Upstream product

• 13482-23-0 4-methoxycyclohexanone 
• 106689-41-2 4-hydrazinylpyridin-2(1H)-one 
• 18068-06-9 4-methoxycyclohexan-1-ol 
• 556-48-9 1,4-Cyclohexanediol 

Downstream Products

• 111380-43-9 1-(3-Dimethylamino-propylamino)-5-methyl-5H-pyrido[4,3-b]indol-8-ol 

Relevant academic research and scientific papers

1-Amino-Substituted 4-Methyl-5H-pyridoindoles (γ-Carbolines) as Tricyclic Analogues of Ellipticines: A New Class of Antineoplastic Agents

A series of 1-amino-substituted 4-methyl-5H-pyridoindoles that are structurally related to ellipticines by deletion of a ring have been synthesized in order to evaluate their DNA affinity, their in vitro cytotoxicity on L1210 cultured cells, and thei

BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME

Inhibitors of BET bromodomains and compositions containing the same are disclosed. Methods of using the BET bromodomain inhibitors in the treatment of diseases and conditions wherein inhibition of BET bromodomain provides a benefit, like cancers, also are disclosed.