2-(1-Benzyl-2-methyl-1H-indol-4-yloxy)-pentanedioic acid 1-methyl ester 5-methyl ester

Base Information

Chemical Name:2-(1-Benzyl-2-methyl-1H-indol-4-yloxy)-pentanedioic acid 1-methyl ester 5-methyl ester
CAS No.:936567-78-1
Molecular Formula:C₂₃H₂₅NO₅
Molecular Weight:395.455
Hs Code.:

Synonyms:2-(1-Benzyl-2-methyl-1H-indol-4-yloxy)-pentanedioic acid 1-methyl ester 5-methyl ester

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Chemical Property of 2-(1-Benzyl-2-methyl-1H-indol-4-yloxy)-pentanedioic acid 1-methyl ester 5-methyl ester

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Technology Process of 2-(1-Benzyl-2-methyl-1H-indol-4-yloxy)-pentanedioic acid 1-methyl ester 5-methyl ester

There total 1 articles about 2-(1-Benzyl-2-methyl-1H-indol-4-yloxy)-pentanedioic acid 1-methyl ester 5-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 760-94-1
dimethyl-2-bromoglutarate

: 172732-78-4
4-hydroxy-2-methyl-1-(phenylmethyl)-1H-indole

: 936567-78-1
2-(1-Benzyl-2-methyl-1H-indol-4-yloxy)-pentanedioic acid 1-methyl ester 5-methyl ester

Guidance literature:: 4-hydroxy-2-methyl-1-(phenylmethyl)-1H-indole; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

dimethyl-2-bromoglutarate; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

Reference yield: 96.0%

: 79-37-8
oxalyl dichloride

: 936567-78-1
2-(1-Benzyl-2-methyl-1H-indol-4-yloxy)-pentanedioic acid 1-methyl ester 5-methyl ester

: 936567-79-2
2-(3-aminooxalyl-1-benzyl-2-methyl-1H-indol-4-yloxy)-pentanedioic acid dimethyl ester

Guidance literature:: oxalyl dichloride; 2-(1-Benzyl-2-methyl-1H-indol-4-yloxy)-pentanedioic acid 1-methyl ester 5-methyl ester; In dichloromethane; at 20 ℃; for 2h;

With ammonia; In dichloromethane; at 20 ℃; for 1.5h;