N,N',N''-triisopropylguanidine

Base Information

• Chemical Name: N,N',N''-triisopropylguanidine
• CAS No.: 121948-77-4
• Molecular Formula: C₁₀H₂₃N₃
• Molecular Weight: 185.313
• Mol file: 121948-77-4.mol

Synonyms:N,N', N''-tri(isopropyl)guanidine

Chemical Property of N,N',N''-triisopropylguanidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N,N'',N''''-Tris(1-methylethyl)guanidine is a useful intermediate in the synthesis and structural investigation of trialkylguanidinato-supported zirconium complexes.

Technology Process of N,N',N''-triisopropylguanidine

There total 2 articles about N,N',N''-triisopropylguanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

isopropylamine (75-31-0) + N′,N″-diisopropyl-N,N-dimethyl guanidine (68897-42-7) → N,N', N''-tri(isopropyl)guanidine (121948-77-4) + dimethyl amine (124-40-3)

Guidance literature:

With [?:η¹:η⁵-(OCH2)(Me2CH2)C2B9H9]Ti(NMe2); at 110 - 115 ℃;

DOI:10.1016/j.jorganchem.2008.11.010

Reference yield:

diisopropyl-carbodiimide (693-13-0) → N-methylpropan-2-amine (4747-21-1) + N,N', N''-tri(isopropyl)guanidine (121948-77-4)

Guidance literature:

With hydrogen; ; In tetrahydrofuran; at 120 ℃; for 29h; under 30002.4 Torr;

DOI:10.1016/0022-328X(88)83091-2

Reference yield: 100.0%

4-chloro-aniline (106-47-8) + N,N', N''-tri(isopropyl)guanidine (121948-77-4) → N-p-chlorophenyl-N', N-diisopropylguanidine

Guidance literature:

With {(Me₂N)C(NiPr)2}2Ti=N(2,6-Me₂C₆H₃); In benzene-d6; at 105 ℃; for 18h;

DOI:10.1021/ja035716j

upstream raw materials:

diisopropyl-carbodiimide

isopropylamine

N′,N″-diisopropyl-N,N-dimethyl guanidine

Downstream raw materials:

1,3-diisopropyl-2-phenylguanidine

bis(N,N',N''-triisopropylguanidinato)bis(benzyl)zirconium

Ta(N(CH₃)2)3[C₆H₁₁NC(NC₆H₁₁)NC₆H₁₁]

[Nb(NMe₂)₂{N(2,6-ⁱPr₂C₆H₃)}{(NⁱPr)₂C(NHⁱPr)}]