2,2-dimethylpropionic acid 4-[(1S,2R)-5-cyano-5-(4-fluorophenyl)-1-(4-fluorophenylamino)-2-(2-oxo-4(S)-phenyloxazolidine-3-carbonyl)-5-trimethylsilyloxypentyl]phenyl ester

Base Information

Chemical Name:2,2-dimethylpropionic acid 4-[(1S,2R)-5-cyano-5-(4-fluorophenyl)-1-(4-fluorophenylamino)-2-(2-oxo-4(S)-phenyloxazolidine-3-carbonyl)-5-trimethylsilyloxypentyl]phenyl ester
CAS No.:1232148-24-1
Molecular Formula:C₄₂H₄₅F₂N₃O₆Si
Molecular Weight:753.918
Hs Code.:

2,2-dimethylpropionic acid 4-[(1S,2R)-5-cyano-5-(4-fluorophenyl)-1-(4-fluorophenylamino)-2-(2-oxo-4(S)-phenyloxazolidine-3-carbonyl)-5-trimethylsilyloxypentyl]phenyl ester

Synonyms:2,2-dimethylpropionic acid 4-[(1S,2R)-5-cyano-5-(4-fluorophenyl)-1-(4-fluorophenylamino)-2-(2-oxo-4(S)-phenyloxazolidine-3-carbonyl)-5-trimethylsilyloxypentyl]phenyl ester

Suppliers and Price of 2,2-dimethylpropionic acid 4-[(1S,2R)-5-cyano-5-(4-fluorophenyl)-1-(4-fluorophenylamino)-2-(2-oxo-4(S)-phenyloxazolidine-3-carbonyl)-5-trimethylsilyloxypentyl]phenyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,2-dimethylpropionic acid 4-[(1S,2R)-5-cyano-5-(4-fluorophenyl)-1-(4-fluorophenylamino)-2-(2-oxo-4(S)-phenyloxazolidine-3-carbonyl)-5-trimethylsilyloxypentyl]phenyl ester

Chemical Property:

Purity/Quality:: NLT 99% ^*data from raw suppliers

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Technology Process of 2,2-dimethylpropionic acid 4-[(1S,2R)-5-cyano-5-(4-fluorophenyl)-1-(4-fluorophenylamino)-2-(2-oxo-4(S)-phenyloxazolidine-3-carbonyl)-5-trimethylsilyloxypentyl]phenyl ester

There total 1 articles about 2,2-dimethylpropionic acid 4-[(1S,2R)-5-cyano-5-(4-fluorophenyl)-1-(4-fluorophenylamino)-2-(2-oxo-4(S)-phenyloxazolidine-3-carbonyl)-5-trimethylsilyloxypentyl]phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 1232148-23-0
2,2-dimethylpropionic acid 4-[(4-fluorophenylimino)methyl]phenyl ester

: 1232148-22-9
2-(4-fluorophenyl)-6-oxo-6-(2-oxo-4(S)-phenyloxazolidin-3-yl)-2-trimethylsilyloxyhexanenitrile

: 1232148-24-1
2,2-dimethylpropionic acid 4-[(1S,2R)-5-cyano-5-(4-fluorophenyl)-1-(4-fluorophenylamino)-2-(2-oxo-4(S)-phenyloxazolidine-3-carbonyl)-5-trimethylsilyloxypentyl]phenyl ester

Guidance literature:: With titanium tetrachloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at -40 ℃; for 1h;

Reference yield: 80.0%

: 1232148-24-1
2,2-dimethylpropionic acid 4-[(1S,2R)-5-cyano-5-(4-fluorophenyl)-1-(4-fluorophenylamino)-2-(2-oxo-4(S)-phenyloxazolidine-3-carbonyl)-5-trimethylsilyloxypentyl]phenyl ester

: 3282-30-2
pivaloyl chloride

: 1232148-25-2
2,2-dimethylpropionic acid 4-{(2S,3R)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-oxoazetidin-2-yl}phenyl ester

Guidance literature:: 2,2-dimethylpropionic acid 4-[(1S,2R)-5-cyano-5-(4-fluorophenyl)-1-(4-fluorophenylamino)-2-(2-oxo-4(S)-phenyloxazolidine-3-carbonyl)-5-trimethylsilyloxypentyl]phenyl ester; With lithium hexamethyldisilazane; In dichloromethane; toluene; at 0 ℃;

With hydrogenchloride; methanol; water; In dichloromethane; water; toluene;

pivaloyl chloride; With triethylamine; In dichloromethane;