3-PHENYL-3-PENTYLAMINE HYDROCHLORIDE

Base Information

• Chemical Name: 3-PHENYL-3-PENTYLAMINE HYDROCHLORIDE
• CAS No.: 104177-96-0
• Molecular Formula: C11H17 N . Cl H
• Molecular Weight: 199.724
• Hs Code.: 2921499090
• Mol file: 104177-96-0.mol

Synonyms:Benzenemethanamine,a,a-diethyl-, hydrochloride (9CI); Benzylamine, a,a-diethyl-, hydrochloride (6CI)

Chemical Property of 3-PHENYL-3-PENTYLAMINE HYDROCHLORIDE

Chemical Property:

• Melting Point: 253 °C
• PSA: 26.02000
• LogP: 4.16290
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

3-Phenylpentan-3-amineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-PHENYL-3-PENTYLAMINE HYDROCHLORIDE

There total 1 articles about 3-PHENYL-3-PENTYLAMINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

ethylmagnesium bromide (925-90-6) + benzonitrile (100-47-0) → α,α-diethylbenzylamine hydrochloride (104177-96-0)

Guidance literature:

ethylmagnesium bromide; benzonitrile; titanium(IV) isopropylate; In diethyl ether; at 20 ℃;

With hydrogenchloride; In diethyl ether; dichloromethane; Further stages.;

DOI:10.1134/S1070428007100016

Reference yield: 47.0%

7,7-dimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylic acid (667921-18-8) + α,α-diethylbenzylamine hydrochloride (104177-96-0) → N-(1-ethyl-1-phenylpropyl)-7,7-dimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]-pyrimidine-3-carboxamide (667925-66-8)

Guidance literature:

7,7-dimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylic acid; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

α,α-diethylbenzylamine hydrochloride; In N,N-dimethyl-formamide; at 80 ℃;

DOI:10.1021/jm101452x

Reference yield:

C16H18ClN3O + α,α-diethylbenzylamine hydrochloride (104177-96-0) → (5R)-N-(1-ethyl-1-phenylpropyl)-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide (791061-65-9)

Guidance literature:

With triethylamine; In toluene; at 70 ℃; for 3h;

DOI:10.1016/j.bmc.2011.02.001

upstream raw materials:

ethylmagnesium bromide

benzonitrile

Downstream raw materials:

(5R)-N-(1-ethyl-1-phenylpropyl)-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide

N-(1-ethyl-1-phenylpropyl)-7,7-dimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]-pyrimidine-3-carboxamide

Refernces