methyl 2-O-benzyl-3,4-dideoxy-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-erythro-hex-3-enopyranoside

Base Information

• Chemical Name: methyl 2-O-benzyl-3,4-dideoxy-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-erythro-hex-3-enopyranoside
• CAS No.: 1096364-46-3
• Molecular Formula: C₄₀H₃₈O₆S
• Molecular Weight: 646.804
• Mol file: 1096364-46-3.mol

Synonyms:methyl 2-O-benzyl-3,4-dideoxy-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-erythro-hex-3-enopyranoside

Chemical Property of methyl 2-O-benzyl-3,4-dideoxy-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-erythro-hex-3-enopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-O-benzyl-3,4-dideoxy-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-erythro-hex-3-enopyranoside

There total 1 articles about methyl 2-O-benzyl-3,4-dideoxy-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-erythro-hex-3-enopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C40H40O7S (1198587-44-8) → methyl 2-O-benzyl-3,4-dideoxy-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-erythro-hex-3-enopyranoside (1096364-46-3)

Guidance literature:

With pyridine; methanesulfonyl chloride; at 0 - 4 ℃; Inert atmosphere;

DOI:10.1002/ejoc.200900553

Reference yield: 90.0%

methyl 2-O-benzyl-3,4-dideoxy-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-erythro-hex-3-enopyranoside (1096364-46-3) + Ethyl isocyanoacetate (2999-46-4) → ethyl (4S,6S,7R)-7-benzyloxy-6-methoxy-4-(triphenylmethyloxymethyl)-2,4,6,7-tetrahydropyrano[3,4-c]pyrrole-1-carboxylat (1096364-61-2)

Guidance literature:

Ethyl isocyanoacetate; With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; Inert atmosphere;

methyl 2-O-benzyl-3,4-dideoxy-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-erythro-hex-3-enopyranoside; In tetrahydrofuran; for 5h; Inert atmosphere; Reflux;

DOI:10.1021/jo801948m

Reference yield: 77.0%

methyl 2-O-benzyl-3,4-dideoxy-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-erythro-hex-3-enopyranoside (1096364-46-3) + malonic acid dimethyl ester (108-59-8) → methyl 2-O-benzyl-3,4-dideoxy-3-C-bis(methoxycarbonyl)methyl-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-glucopyranoside (1198587-46-0)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; Inert atmosphere; Reflux;

DOI:10.1002/ejoc.200900553

upstream raw materials:

C₄₀H₄₀O₇S

Downstream raw materials:

ethyl (4S,6S,7R)-7-benzyloxy-6-methoxy-4-(triphenylmethyloxymethyl)-2,4,6,7-tetrahydropyrano[3,4-c]pyrrole-1-carboxylat

methyl 2-O-benzyl-3-C-nitromethyl-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-glucopyranoside

methyl 2-O-benzyl-3,4-dideoxy-3-C-bis(methoxycarbonyl)methyl-4-(4-methylphenyl)sulfonyl-6-O-triphenylmethyl-α-D-glucopyranoside