Ethyl 4-acetamidosalicylate

Base Information

Chemical Name:Ethyl 4-acetamidosalicylate
CAS No.:22776-13-2
Molecular Formula:C₁₁H₁₃NO₄
Molecular Weight:223.229
Hs Code.:
DSSTox Substance ID:DTXSID201216529

Synonyms:Ethyl 4-acetamidosalicylate;SCHEMBL5925538;HHELDUHJNXALMI-UHFFFAOYSA-N;DTXSID201216529;22776-13-2;Benzoic acid, 4-(acetylamino)-2-hydroxy-, ethyl ester

Suppliers and Price of Ethyl 4-acetamidosalicylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Ethyl 4-acetamidosalicylate

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:223.08445790
Heavy Atom Count:16
Complexity:267

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=C(C=C(C=C1)NC(=O)C)O

Technology Process of Ethyl 4-acetamidosalicylate

There total 5 articles about Ethyl 4-acetamidosalicylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 6059-17-2
ethyl 4-amino-2-hydroxybenzoate

: 108-24-7
acetic anhydride

: 22776-13-2
ethyl 4-acetylamino-o-hydroxybenzoate

Guidance literature:: With sulfuric acid; In ethanol; at 50 ℃; for 4h; Inert atmosphere;
DOI:10.1002/chem.201200610

Reference yield:

: 65-49-6
4-Aminosalicylic acid

: 22776-13-2
ethyl 4-acetylamino-o-hydroxybenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 6 h / Reflux

2: sulfuric acid / ethanol / 4 h / 50 °C / Inert atmosphere

With sulfuric acid; In ethanol;
DOI:10.1002/chem.201200610