4-Methyl-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene

Base Information

• Chemical Name: 4-Methyl-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene
• CAS No.: 136053-37-7
• Molecular Formula: C₁₅H₂₄Si₂
• Molecular Weight: 260.527
• Mol file: 136053-37-7.mol

Synonyms:4-Methyl-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene

Chemical Property of 4-Methyl-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-Methyl-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene

There total 6 articles about 4-Methyl-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1,4-bis(trimethylsilyl)-1,3-butadiyne (4526-07-2) + 2-methylbut-1-en-3-yne (78-80-8) → 4-Methyl-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene (136053-37-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; Heating;

DOI:10.1021/ja971935r

Reference yield:

1,4-bis(trimethylsilyl)-1,3-butadiyne (4526-07-2) + isoprene (78-79-5,9003-31-0) → trimethyl-[(4-methyl-2-(trimethylsilyl)ethynyl)phenyl]silan (136053-38-8) + 4-Methyl-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene (136053-37-7)

Guidance literature:

1,4-bis(trimethylsilyl)-1,3-butadiyne; isoprene; With CoBr₂(1,2-bis-diphenylphosphinoethane); zinc(II) iodide; zinc; In dichloromethane; at 20 ℃; for 16h; Inert atmosphere;

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In benzene; for 1h; regioselective reaction;

DOI:10.1021/ol802837m

Reference yield:

2-bromo-4-methyl-1-[2-(trimethylsilyl)ethynyl]benzene (935223-82-8) + chloro-trimethyl-silane (75-77-4) → 4-Methyl-2-trimethylsilanyl-1-trimethylsilanylethynyl-benzene (136053-37-7)

Guidance literature:

2-bromo-4-methyl-1-[2-(trimethylsilyl)ethynyl]benzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.166667h;

chloro-trimethyl-silane; In tetrahydrofuran; at -78 - 20 ℃; for 1h;

DOI:10.1002/anie.201400828

upstream raw materials:

chloro-trimethyl-silane

4-n-methylphenylacetylene

1,4-bis(trimethylsilyl)-1,3-butadiyne

2-methylbut-1-en-3-yne