4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzoic acid

Base Information

Chemical Name:4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzoic acid
CAS No.:1095275-07-2
Molecular Formula:C₁₈H₁₃Cl₂F₃O₄
Molecular Weight:421.2
Hs Code.:

Synonyms:4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzoic acid

Suppliers and Price of 4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzoic acid

Chemical Property:

Purity/Quality:: >98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzoic acid

There total 2 articles about 4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55860-35-0
4-acetyl-2-methyl benzoic acid

: 130336-16-2
3,5-dichloro-2,2,2-trifluoroacetophenone

: 1095275-07-2
4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzoic acid

Guidance literature:: With Sodium laurate; potassium carbonate; In water; at 60 ℃; for 9h;

Reference yield:

: 68837-59-2
4-bromo-2-methylbenzoic acid

: 1095275-07-2
4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1,3-bis-(diphenylphosphino)propane; palladium diacetate; potassium carbonate / butan-1-ol / 90 °C / Inert atmosphere

2: potassium carbonate; dodecanoic acid sodium salt / lithium hydroxide monohydrate / 24 h / 60 °C

With 1,3-bis-(diphenylphosphino)propane; dodecanoic acid sodium salt; palladium diacetate; potassium carbonate; In lithium hydroxide monohydrate; butan-1-ol; 1: |Suzuki Coupling;