(R)-1-Benzoyl-2-(tert-butyl)-3-methylimidazolidin-4-one

Base Information

Chemical Name:(R)-1-Benzoyl-2-(tert-butyl)-3-methylimidazolidin-4-one
CAS No.:101055-57-6
Molecular Formula:C15H20 N2 O2
Molecular Weight:260.33
Hs Code.:2933 29 90
European Community (EC) Number:634-441-0
Nikkaji Number:J2.521.404H
Mol file:101055-57-6.mol

Synonyms:101055-57-6;(R)-1-Benzoyl-2-(tert-butyl)-3-methylimidazolidin-4-one;4-IMidazolidinone, 1-benzoyl-2-(1,1-diMethylethyl)-3-Methyl-, (2R)-;(2R)-(-)-1-Benzoyl-2-tert-butyl-3-methyl-4-imidazolidinone;SCHEMBL9706890;(2R)-1-Benzoyl-2-tert-butyl-3-methyl-4-imidazolidinone;4-IMidazolidinone,1-benzoyl-2-(1,1-diMethylethyl)-3-Methyl-,(2R)-

Suppliers and Price of (R)-1-Benzoyl-2-(tert-butyl)-3-methylimidazolidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(2R)-(-)-1-Benzoyl-2-tert-butyl- 3-methyl-4-imidazolidinon for synthesis. CAS 101055-57-6, molar mass 260.33 g/mol., for synthesis
8141670001
$ 110.00

Sigma-Aldrich
(2R)-(-)-1-Benzoyl-2-tert-butyl- 3-methyl-4-imidazolidinon for synthesis
1 g
$ 105.45

American Custom Chemicals Corporation
(2R)-(-)-1-BENZOYL-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE 95.00%
5MG
$ 496.45

Total 5 raw suppliers

Chemical Property of (R)-1-Benzoyl-2-(tert-butyl)-3-methylimidazolidin-4-one

Chemical Property:

Melting Point:144-147°C
Boiling Point:425.3±38.0 °C(Predicted)
PKA:-0.70±0.40(Predicted)
PSA：40.62000
Density:1.128±0.06 g/cm3(Predicted)
LogP:1.84880
Storage Temp.:2-8°C
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:260.152477885
Heavy Atom Count:19
Complexity:367

Purity/Quality:

≥95% ^*data from raw suppliers

(2R)-(-)-1-Benzoyl-2-tert-butyl- 3-methyl-4-imidazolidinon for synthesis. CAS 101055-57-6, molar mass 260.33 g/mol., for synthesis ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1N(C(=O)CN1C(=O)C2=CC=CC=C2)C
Isomeric SMILES:CC(C)(C)[C@@H]1N(C(=O)CN1C(=O)C2=CC=CC=C2)C

Technology Process of (R)-1-Benzoyl-2-(tert-butyl)-3-methylimidazolidin-4-one

There total 8 articles about (R)-1-Benzoyl-2-(tert-butyl)-3-methylimidazolidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 137348-68-6
(R)-1-benzoyl-2-tert-butyl-3(H)-1,3-imidazolidin-4-one

: 77-78-1
dimethyl sulfate

: 101055-57-6
(2R)-1-benzoyl-2-(1,1-dimethylethyl)-3-methyl-4-imidazolidinone

Guidance literature:: With sodium hydroxide; In acetonitrile; at 55 ℃; for 2h;
DOI:10.1016/S0957-4166(00)80465-6

Reference yield: 45.0%

: 98-88-4
benzoyl chloride

: 101143-57-1
(S)-2-(t-Butyl)-3-methyl-4-imidazolidinone

: 101055-57-6
(2R)-1-benzoyl-2-(1,1-dimethylethyl)-3-methyl-4-imidazolidinone

Guidance literature:: With sodium hydroxide; In dichloromethane;

Reference yield:

: 137348-64-2
2-N-(2,2'-dimethylpropyliden)amino-N'-(α-phenylethyl)acetamide

: 101055-57-6
(2R)-1-benzoyl-2-(1,1-dimethylethyl)-3-methyl-4-imidazolidinone

Guidance literature:: Multi-step reaction with 3 steps

1: 7 h / Heating

2: 41 percent / H₂, acetic acid / 20percent Pd/C / ethanol / 72 h / 50 - 60 °C / 18240 - 22800 Torr

3: 77 percent / NaOH / acetonitrile / 2 h / 55 °C

With sodium hydroxide; hydrogen; acetic acid; palladium on activated charcoal; In ethanol; acetonitrile;
DOI:10.1016/S0957-4166(00)80465-6