(R)-1-(4-methoxyphenyl)-2-( pyridin-2-yl)ethanol

Base Information

Chemical Name:(R)-1-(4-methoxyphenyl)-2-( pyridin-2-yl)ethanol
CAS No.:1007107-45-0
Molecular Formula:C₁₄H₁₅NO₂
Molecular Weight:229.279
Hs Code.:

Synonyms:(R)-1-(4-methoxyphenyl)-2-( pyridin-2-yl)ethanol

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Chemical Property of (R)-1-(4-methoxyphenyl)-2-( pyridin-2-yl)ethanol

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Technology Process of (R)-1-(4-methoxyphenyl)-2-( pyridin-2-yl)ethanol

There total 8 articles about (R)-1-(4-methoxyphenyl)-2-( pyridin-2-yl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 10420-97-0
1-(4-methoxyphenyl)-2-(pyridin-2-yl)ethanone

: 1007107-45-0
(R)-1-(4-methoxyphenyl)-2-( pyridin-2-yl)ethanol

Guidance literature:: With ketoreductases P₂-G₀₃; nicotinamide adenine dinucleotide phosphate; magnesium sulfate; isopropyl alcohol; In aq. phosphate buffer; at 30 ℃; for 24h; pH=7; Reagent/catalyst; enantioselective reaction; Enzymatic reaction;
DOI:10.1039/c9ob01616c

Reference yield: 40.0%

: 73853-36-8
2-<2-Hydroxy-2-(-p-methoxyphenyl)ethyl>pyridine

: 1227475-37-7
bis(3,5-dimethylphenyl)(methyl)silane

: 1007107-45-0
(R)-1-(4-methoxyphenyl)-2-( pyridin-2-yl)ethanol

: (R)-2-(2-[bis(3,5-dimethylphenyl)methylsilanyloxy]-2-(4-methoxyphenyl)ethyl)pyridine

: 1227475-53-7
(S)-2-(2-[bis(3,5-dimethylphenyl)methylsilanyloxy]-2-(4-methoxyphenyl)ethyl)pyridine

Guidance literature:: With (3aR,8aR)-6-t-butyl-2,2-dimethyl-4,4,8,8-tetra(naphthalen-2-yl)tetrahydro[1,3]dioxolo[4,5-e]-[1,3,2]dioxaphosphepine; caesium carbonate; copper(l) chloride; In tetrahydrofuran; at 20 ℃; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1002/anie.200905561

Reference yield:

: 851542-50-2
(SiR)-1-tert-butyl-1,2,3,4-tetrahydro-1-silanaphthalene

: 73853-36-8
2-<2-Hydroxy-2-(-p-methoxyphenyl)ethyl>pyridine

: 1007107-45-0
(R)-1-(4-methoxyphenyl)-2-( pyridin-2-yl)ethanol

: C₂₇H₃₃NO₂Si

: 1007107-39-2
C₂₇H₃₃NO₂Si

Guidance literature:: With N,N′-bis(2,6-diisopropylphenyl)imidazol-2-ylidene hydrochloride; potassium tert-butylate; bis(1,5-cyclooctadiene)rhodium(I) trifluoromethanesulfonate; In toluene; at 50 ℃;
DOI:10.1002/anie.200703847