2-cyano-4-n-pentylanisole

Base Information

• Chemical Name: 2-cyano-4-n-pentylanisole
• CAS No.: 78626-42-3
• Molecular Formula: C₁₃H₁₇NO
• Molecular Weight: 203.284
• Mol file: 78626-42-3.mol

Synonyms:2-cyano-4-n-pentylanisole

Chemical Property of 2-cyano-4-n-pentylanisole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-cyano-4-n-pentylanisole

There total 3 articles about 2-cyano-4-n-pentylanisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

copper(I) cyanide (544-92-3) + 2-bromo-1-methoxy-4-pentylbenzene (78626-44-5) → 2-cyano-4-n-pentylanisole (78626-42-3)

Guidance literature:

In N,N-dimethyl-formamide; for 5h; Heating;

DOI:10.1080/00268948108074677

Reference yield:

1-(4-Methoxyphenyl)pentane (20056-58-0) → 2-cyano-4-n-pentylanisole (78626-42-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate, bromine / acetic acid; methanol / 3 h / 0 °C

2: 65 percent / dimethylformamide / 5 h / Heating

With bromine; sodium acetate; In methanol; acetic acid; N,N-dimethyl-formamide;

DOI:10.1080/00268948108074677

Reference yield:

n-valeryl chloride (638-29-9) → 2-cyano-4-n-pentylanisole (78626-42-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 87 percent / AlCl₃ / CCl₄ / 2 h / 0 °C

2: 75 percent / 80percent hydrazine hydrate, KOH / bis-(2-hydroxy-ethyl) ether / 3 h / Heating

3: sodium acetate, bromine / acetic acid; methanol / 3 h / 0 °C

4: 65 percent / dimethylformamide / 5 h / Heating

With potassium hydroxide; aluminium trichloride; bromine; sodium acetate; hydrazine hydrate; In methanol; tetrachloromethane; acetic acid; N,N-dimethyl-formamide; diethylene glycol;

DOI:10.1080/00268948108074677

upstream raw materials:

copper(I) cyanide

2-bromo-1-methoxy-4-pentylbenzene

1-(4-Methoxyphenyl)pentane

n-valeryl chloride

Downstream raw materials:

2-cyano 4-n-pentylbutylphenol