Technology Process of Diethyl-(4-propylphenyl)malonat
There total 4 articles about Diethyl-(4-propylphenyl)malonat which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
2-Picolinic acid; copper(l) iodide; caesium carbonate;
In
tetrahydrofuran;
at 70 ℃;
for 6h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) potassium t-butoxide / 2.) dichlorobis(triphenylphosphine)palladium / 1.) 1,2-dimethoxyethane, room temperature, 10 min, 2.) 1,2-dimethoxyethane, 70 deg C, 8 h
2: concd. hydrochloric acid, calcium chloride / benzene / 1.) room temperature, 3 h, 2.) 55 deg C, 2 h, 3.) reflux, 5 h
With
hydrogenchloride; potassium tert-butylate; calcium chloride;
bis-triphenylphosphine-palladium(II) chloride;
In
benzene;
DOI:10.1246/bcsj.62.3896
- Guidance literature:
-
With
hydrogenchloride; calcium chloride;
In
benzene;
1.) room temperature, 3 h, 2.) 55 deg C, 2 h, 3.) reflux, 5 h;
DOI:10.1246/bcsj.62.3896
