2,2’-(1,3-Propanediyldioxy)bisbenzaldehyde

Base Information

• Chemical Name: 2,2’-(1,3-Propanediyldioxy)bisbenzaldehyde
• CAS No.: 17954-12-0
• Molecular Formula: C17H16 O4
• Molecular Weight: 284.312
• DSSTox Substance ID: DTXSID30390784
• Nikkaji Number: J1.404.960F
• Wikidata: Q82187810
• Mol file: 17954-12-0.mol

Synonyms:Benzaldehyde,2,2'-(trimethylenedioxy)di- (6CI,8CI); 1,3-Bis(2-formylphenoxy)propane;1,3-Bis(o-formylphenoxy)propane; 1,5-Bis(2'-formylphenyl)-1,5-dioxapentane;2,2'-(Propane-1,3-diyldioxy)dibenzaldehyde

Chemical Property of 2,2’-(1,3-Propanediyldioxy)bisbenzaldehyde

Chemical Property:

• Melting Point: 97-98 °C
• Boiling Point: 467.1±25.0 °C(Predicted)
• PSA: 52.60000
• Density: 1.193±0.06 g/cm3(Predicted)
• LogP: 3.15950
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 284.10485899
• Heavy Atom Count: 21
• Complexity: 288

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C=O)OCCCOC2=CC=CC=C2C=O

Technology Process of 2,2’-(1,3-Propanediyldioxy)bisbenzaldehyde

There total 9 articles about 2,2’-(1,3-Propanediyldioxy)bisbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

salicylaldehyde (90-02-8) + 1,3-dibromo-propane (109-64-8) → 2-[3-(2-formylphenoxy)propoxy]benzaldehyde (17954-12-0)

Guidance literature:

salicylaldehyde; With potassium hydroxide; In tetrahydrofuran; dimethyl sulfoxide; for 0.5h; Reflux;

1,3-dibromo-propane; In tetrahydrofuran; dimethyl sulfoxide; for 16h; Reflux;

DOI:10.1007/s00706-017-2125-3

Reference yield: 80.0%

potassium 2-formylphenolate (33838-32-3) + 1,3-dibromo-propane (109-64-8) → 2-[3-(2-formylphenoxy)propoxy]benzaldehyde (17954-12-0)

Guidance literature:

In N,N-dimethyl-formamide; for 3h; Reflux;

DOI:10.1080/15533174.2012.754770

Reference yield: 70.0%

2-methyl-benzyl alcohol (89-95-2) + 1,3-dibromo-propane (109-64-8) → 2-[3-(2-formylphenoxy)propoxy]benzaldehyde (17954-12-0)

Guidance literature:

2-methyl-benzyl alcohol; With potassium hydroxide; In ethanol; Heating;

1,3-dibromo-propane; In N,N-dimethyl-formamide; for 0.0833333h; Heating;

DOI:10.3390/11060469

upstream raw materials:

salicylaldehyde

1,3-dibromo-propane

2-methyl-benzyl alcohol

1,3-dimesyloxypropane

Downstream raw materials:

2,2'-propanediyldioxy-di-benzaldehyde bis-phenylimine

2-[Hydroxy-(2-{3-[2-(1-hydroxy-2-methoxycarbonyl-allyl)-phenoxy]-propoxy}-phenyl)-methyl]-acrylic acid methyl ester

C₂₅H₂₆N₆O₈

3,23-diphenyl-12,13,27,28-tetrahydro-14H,29H-bis[1,2,4]triazolo[4,3-f:3,4-m]dibenzo[b,q][1,19]dioxa[8,12]dithia[5,6,14,15]tetraazacyclodocosine