3,23-diphenyl-12,13,27,28-tetrahydro-14H,29H-bis[1,2,4]triazolo[4,3-f:3,4-m]dibenzo[b,q][1,19]dioxa[8,12]dithia[5,6,14,15]tetraazacyclodocosine

Base Information

• Chemical Name: 3,23-diphenyl-12,13,27,28-tetrahydro-14H,29H-bis[1,2,4]triazolo[4,3-f:3,4-m]dibenzo[b,q][1,19]dioxa[8,12]dithia[5,6,14,15]tetraazacyclodocosine
• CAS No.: 178384-04-8
• Molecular Formula: C₃₆H₃₂N₈O₂S₂
• Molecular Weight: 672.834
• Mol file: 178384-04-8.mol

Synonyms:

Chemical Property of 3,23-diphenyl-12,13,27,28-tetrahydro-14H,29H-bis[1,2,4]triazolo[4,3-f:3,4-m]dibenzo[b,q][1,19]dioxa[8,12]dithia[5,6,14,15]tetraazacyclodocosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,23-diphenyl-12,13,27,28-tetrahydro-14H,29H-bis[1,2,4]triazolo[4,3-f:3,4-m]dibenzo[b,q][1,19]dioxa[8,12]dithia[5,6,14,15]tetraazacyclodocosine

There total 5 articles about 3,23-diphenyl-12,13,27,28-tetrahydro-14H,29H-bis[1,2,4]triazolo[4,3-f:3,4-m]dibenzo[b,q][1,19]dioxa[8,12]dithia[5,6,14,15]tetraazacyclodocosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

2-[3-(2-formylphenoxy)propoxy]benzaldehyde (17954-12-0) + 1,3-bis(4-amino-5-phenyl-1,2,4-triazol-3-ylsulfanyl)propane (178384-14-0) → 3,23-diphenyl-12,13,27,28-tetrahydro-14H,29H-bis[1,2,4]triazolo[4,3-f:3,4-m]dibenzo[b,q][1,19]dioxa[8,12]dithia[5,6,14,15]tetraazacyclodocosine (178384-04-8)

Guidance literature:

With acetic acid; for 2h; Heating;

Reference yield: 8.0%

1,3-dibromo-propane (109-64-8) + 1,3-bis(4-o-hydroxybenzylideneamino-5-phenyl-1,2,4-triazol-3-ylsulfanyl)propane (178384-28-6) → 3,23-diphenyl-12,13,27,28-tetrahydro-14H,29H-bis[1,2,4]triazolo[4,3-f:3,4-m]dibenzo[b,q][1,19]dioxa[8,12]dithia[5,6,14,15]tetraazacyclodocosine (178384-04-8)

Guidance literature:

With sodium ethanolate; In ethanol; for 6h; Heating;

Reference yield:

3-phenyl-4-amino-5-mercapto-1,2,4-triazole (22706-11-2) → 3,23-diphenyl-12,13,27,28-tetrahydro-14H,29H-bis[1,2,4]triazolo[4,3-f:3,4-m]dibenzo[b,q][1,19]dioxa[8,12]dithia[5,6,14,15]tetraazacyclodocosine (178384-04-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / aq. NaOH / aq. ethanol / 1 h / Heating

2: 48 percent / glacial AcOH / 2 h / Heating

With sodium hydroxide; acetic acid; In ethanol;

upstream raw materials:

2-[3-(2-formylphenoxy)propoxy]benzaldehyde

1,3-bis(4-amino-5-phenyl-1,2,4-triazol-3-ylsulfanyl)propane

1,3-dibromo-propane

1,3-bis(4-o-hydroxybenzylideneamino-5-phenyl-1,2,4-triazol-3-ylsulfanyl)propane