(R)-(+)-endo-2-norbornyl acetate

Base Information

• Chemical Name: (R)-(+)-endo-2-norbornyl acetate
• CAS No.: 112836-13-2
• Molecular Formula: C₉H₁₄O₂
• Molecular Weight: 154.209
• Mol file: 112836-13-2.mol

Synonyms:(R)-(+)-endo-2-norbornyl acetate

Chemical Property of (R)-(+)-endo-2-norbornyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-(+)-endo-2-norbornyl acetate

There total 17 articles about (R)-(+)-endo-2-norbornyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

(+/-)-endo-2-norborneol (497-36-9) + acetic acid (64-19-7,77671-22-8) → (+/-)-endo-norborneol acetate (29583-33-3,34640-76-1,36914-56-4,54325-10-9,54325-11-0,54656-95-0,112836-13-2,112836-20-1)

Guidance literature:

With iodine; at 85 ℃; for 2.5h;

DOI:10.1016/j.tetlet.2009.02.224

Reference yield: 49.0%

vinyl acetate (108-05-4,9003-20-7) + (+/-)-endo-2-norborneol (497-36-9) → endo-norborneol (497-36-9,36779-79-0) + (R)-(+)-endo-2-norbornyl acetate (112836-13-2)

Guidance literature:

With porcine pancreatic lipase; In tert-butyl methyl ether; at 37 ℃; for 72h; optical yield given as %ee; Enzymatic reaction;

DOI:10.1002/chir.20739

Reference yield: 23.8%

(+)-(1S,2S,4R)-2-norbornylamine (84235-33-6) + acetic acid (64-19-7,77671-22-8) → (R)-(+)-endo-2-norbornyl acetate (112836-13-2) + exo-2-norbornanol (497-37-0) + (+-)-2exo-acetoxy-norbornane (34640-76-1) + Bicyclo<2.2.1>hept-exo-2-ylnitrat (21301-95-1,54894-23-4,111423-44-0)

Guidance literature:

With sodium nitrite; for 12h; Product distribution; Mechanism; Ambient temperature; influence of the polarity of the solvent on yields and enantiomeric purity;

DOI:10.1021/ja00342a051

upstream raw materials:

acetic acid

Isopropenyl acetate

(+/-)-endo-2-norborneol

endo-2-aminonorbornane

Downstream raw materials:

(+/-)-endo-2-norborneol

(+/-)-3,5-dinitro-benzoic acid-[2endo]norbornyl ester

(+/-)-phthalic acid mono-[2endo]norbornyl ester

Norbornan-2-on