ALLYL 2-BROMOBENZYL ETHER 95

Base Information

• Chemical Name: ALLYL 2-BROMOBENZYL ETHER 95
• CAS No.: 87280-01-1
• Molecular Formula: C₁₀H₁₁BrO
• Molecular Weight: 227.101
• Mol file: 87280-01-1.mol

Synonyms:1-((allyloxy)methyl)-2-bromobenzene

Chemical Property of ALLYL 2-BROMOBENZYL ETHER 95

Chemical Property:

• Vapor Pressure: 0.024mmHg at 25°C
• Refractive Index: n20/D 1.5460(lit.)
• Boiling Point: 251-252?°C(lit.)
• Flash Point: >230?°F
• Density: 1.327?g/mL?at 25?°C(lit.)

Purity/Quality:

98%Min ^*data from raw suppliers

ALLYL-2-BROMOBENZYL ETHER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ALLYL 2-BROMOBENZYL ETHER 95

There total 3 articles about ALLYL 2-BROMOBENZYL ETHER 95 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

o-bromobenzyl alcohol (18982-54-2) + allyl bromide (106-95-6) → 1-((allyloxy)methyl)-2-bromobenzene (87280-01-1)

Guidance literature:

o-bromobenzyl alcohol; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 1h; Sonication;

allyl bromide; In tetrahydrofuran; at 20 ℃; Sonication;

DOI:10.1002/anie.201907226

Reference yield: 78.0%

allyl alcohol (107-18-6) + 1-Bromo-2-bromomethyl-benzene (3433-80-5) → 1-((allyloxy)methyl)-2-bromobenzene (87280-01-1)

Guidance literature:

With sodium; for 2h; Heating;

DOI:10.1021/jo00170a005

Reference yield:

o-bromobenzyl alcohol (18982-54-2) + 3-chloroprop-1-ene (107-05-1) → 1-((allyloxy)methyl)-2-bromobenzene (87280-01-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1002/(sici)1099-0690(199908)1999:8<1885::aid-ejoc1885>3.0.co;2-u

upstream raw materials:

allyl alcohol

1-Bromo-2-bromomethyl-benzene

o-bromobenzyl alcohol

allyl bromide

Downstream raw materials:

3-((2-bromobenzyl)oxy)propan-1-ol

benzyl allyl ether

2-methylchromene

(4S,6S)-8-(2-Bromo-benzyloxy)-4-(tert-butyl-dimethyl-silanyloxy)-6-(tetrahydro-pyran-2-yloxy)-octan-2-one

Refernces

• 1、 -. "SYNTHESIS OF A TRIANGULENE RING SYSTEM AND DERIVATIVES THEREOF". Paragraph 0011; 0019. . Retrieved 2021/02/12.
• 2、 Braun, Alain,Cho, Ii Hwan,Ciblat, Stephane,Clyne, Dean,Forgione, Pat,Hart, Amy C.,Huang, Guoxiang,Kim, Jungchul,Modolo, Isabelle,Paquette, Leo A.,Peng, Xiaowen,Pichlmair, Stefan,Stewart, Catherine A.,Wang, Jizhou,Zuev, Dmitry. "Enantioselective synthesis of structurally intricate and complementary polyoxygenated building blocks of spongistatin 1 (altohyrtin a)". experimental part. p. 651 - 769. Retrieved 2010/02/27.