Technology Process of ethyl 2-(3,5-bis(benzyloxy)-2-(hex-5-enoyl)phenyl)acetate
There total 9 articles about ethyl 2-(3,5-bis(benzyloxy)-2-(hex-5-enoyl)phenyl)acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
caesium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 1h;
Inert atmosphere;
DOI:10.1021/ol2011117
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: diisobutylaluminium hydride / hexane; dichloromethane / 1 h / -78 - 0 °C / Inert atmosphere
1.2: 0.5 h / -78 - 20 °C / Inert atmosphere
2.1: tetra-n-propylammonium perruthenate.; 4-methylmorpholine N-oxide / dichloromethane / 1.5 h / 20 °C / Inert atmosphere; Molecular sieve
3.1: magnesium / tetrahydrofuran / 0 °C / Inert atmosphere
3.2: 0.17 h / 0 °C / Inert atmosphere
4.1: Jones reagent / acetone / 2 h / 0 - 20 °C / Inert atmosphere
5.1: caesium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere
With
Jones reagent; tetra-n-propylammonium perruthenate.; diisobutylaluminium hydride; caesium carbonate; magnesium; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1021/ol2011117
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Jones reagent / acetone / 2 h / 0 - 20 °C / Inert atmosphere
2: caesium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere
With
Jones reagent; caesium carbonate;
In
N,N-dimethyl-formamide; acetone;
DOI:10.1021/ol2011117