2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide

Base Information

Chemical Name:2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide
CAS No.:865458-58-8
Molecular Formula:C₂₁H₂₃N₃O
Molecular Weight:333.433
Hs Code.:

Synonyms:2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide

Suppliers and Price of 2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide

There total 1 articles about 2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 6-bromo-2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline hydrochloride

: 201230-82-2
carbon monoxide

: 124-40-3
dimethyl amine

: 865458-58-8
2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide

Guidance literature:: With triethylamine; triphenylphosphine; palladium diacetate; In tetrahydrofuran; at 120 ℃; for 19h; under 4500.45 Torr;
DOI:10.1016/j.bmc.2007.08.065

Reference yield: 89.0%

: 865458-58-8
2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide

: 3-bromo-2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide

Guidance literature:: With N-Bromosuccinimide; In dichloromethane; at -75 ℃; for 1h;
DOI:10.1016/j.bmc.2007.08.065

Reference yield: 78.0%

: 865458-58-8
2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide

: 3-formyl-2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide

Guidance literature:: 2-methyl-9-phenyl-7,8,9,10-tetrahydro-imidazo[2,1-a]isoquinoline-6-carboxylic acid dimethylamide; With trichlorophosphate; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 5.5h;

With ammonia; In dichloromethane; water; at 0 ℃;