Boc-Val-Cit-PABA

Base Information

Chemical Name:Boc-Val-Cit-PABA
CAS No.:870487-09-5
Molecular Formula:C₂₃H₃₇N₅O₆
Molecular Weight:479.577
Hs Code.:
Mol file:870487-09-5.mol

Synonyms:tert-butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentane-2-yl)amino)-3-methyl-1-oxobutane-2-yl)carbamate

Suppliers and Price of Boc-Val-Cit-PABA

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynChem
Boc-Val-Cit-PAB-OH 95+%
1 g
$ 395.00

Iris Biotech GmbH
Boc-Val-Cit-PAB
250 mg
$ 303.75

Iris Biotech GmbH
Boc-Val-Cit-PAB
1 g
$ 877.50

ChemScene
Boc-Val-Cit-PAB
100mg
$ 362.00

BroadPharm
Boc-Val-Cit-PAB 95%
1 G
$ 740.00

BroadPharm
Boc-Val-Cit-PAB 95%
500 MG
$ 480.00

BroadPharm
Boc-Val-Cit-PAB 95%
250 MG
$ 280.00

Acrotein
Boc-Val-Cit-PABA 97%
0.1g
$ 366.67

Total 15 raw suppliers

Chemical Property of Boc-Val-Cit-PABA

Chemical Property:

Boiling Point:771.3±60.0 °C(Predicted)
PKA:11.25±0.46(Predicted)
Density:1.209±0.06 g/cm3(Predicted)
Storage Temp.:2-8°C

Purity/Quality:

98% ^*data from raw suppliers

Boc-Val-Cit-PAB-OH 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Boc-Val-Cit-PAB is a cleavable ADC linker. The Val-Cit peptide will specifically be cleaved by Cathepsin B. Boc group can be removed under acidic condition.

Technology Process of Boc-Val-Cit-PABA

There total 13 articles about Boc-Val-Cit-PABA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.06%

: 870487-08-4
(6S,9S)-1-amino-9-isopropyl-13,13-dimethyl-1,8,11-trioxo-12-oxa-2,7,10-triazatetradecane-6-carboxylic acid

: 623-04-1
4-aminobenzenemethanol

: 870487-09-5
tert-butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentane-2-yl)amino)-3-methyl-1-oxobutane-2-yl)carbamate

Guidance literature:: With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In methanol; dichloromethane; at 25 ℃; for 8h; Darkness;

Reference yield: 71.0%

: 870487-09-5
tert-butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentane-2-yl)amino)-3-methyl-1-oxobutane-2-yl)carbamate

Guidance literature:

Reference yield:

: 13734-41-3
t-Boc-L-valine

: 1037794-22-1
(S)-2-amino-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide

: 870487-09-5
tert-butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentane-2-yl)amino)-3-methyl-1-oxobutane-2-yl)carbamate

Guidance literature:: t-Boc-L-valine; With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

(S)-2-amino-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 16h;