beta-Estradiol 3,17-disulfate dipotassium salt

Base Information

Chemical Name:beta-Estradiol 3,17-disulfate dipotassium salt
CAS No.:17046-60-5
Molecular Formula:C18H24 O8 S2 . 2 K
Molecular Weight:508.696
Hs Code.:
DSSTox Substance ID:DTXSID80585143
Mol file:17046-60-5.mol

Synonyms:17046-60-5;beta-Estradiol 3,17-disulfate dipotassium salt;1,3,5[10]-ESTRATRIENE-3,17beta-DIOL DISULFATE DIPOTASSIUM SALT;DTXSID80585143;PUBCHEM_16219305;CID 16219305;beta-Estradiol 3,17-disulfate dipotassium salt, >=95%

Suppliers and Price of beta-Estradiol 3,17-disulfate dipotassium salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
β-Estradiol 3,17-disulfate dipotassium salt
500mg
$ 1260.00

Sigma-Aldrich
β-Estradiol 3,17-disulfate dipotassium salt ≥95%
100mg
$ 326.00

American Custom Chemicals Corporation
BETA-ESTRADIOL-3,17-DISULFATE DIPOTASSIUM SALT 95.00%
100MG
$ 902.90

American Custom Chemicals Corporation
BETA-ESTRADIOL-3,17-DISULFATE DIPOTASSIUM SALT 95.00%
25MG
$ 704.25

Total 6 raw suppliers

Chemical Property of beta-Estradiol 3,17-disulfate dipotassium salt

Chemical Property:

PSA：143.96000
LogP:5.18640
Storage Temp.:−20°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:471.05496655
Heavy Atom Count:29
Complexity:798

Purity/Quality:

98%,99%, ^*data from raw suppliers

β-Estradiol 3,17-disulfate dipotassium salt ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2OS(=O)(=O)O)CCC4=C3C=CC(=C4)OS(=O)(=O)O.[K]
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2OS(=O)(=O)O)CCC4=C3C=CC(=C4)OS(=O)(=O)O.[K]
Uses β-Estradiol 3,17-Disulfate Dipotassium Salt in Ehrlich ascites tumor cells, increases equilibrium distribution rations by inhibiting efflux without an appreciable action on influx of amino acids.

Technology Process of beta-Estradiol 3,17-disulfate dipotassium salt

There total 2 articles about beta-Estradiol 3,17-disulfate dipotassium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 105546-92-7
3,17β-Di-sulfooxyestra-1,3,5(10)-triene di-triethylammonium salt

: 17046-60-5
17β-estradiol-3,17-disulfate potassium salt

Guidance literature:: With potassium hydroxide; In methanol;

Reference yield:

: 50-28-2
estradiol

: 17046-60-5
17β-estradiol-3,17-disulfate potassium salt

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 2 h / 90 - 95 °C

2: potassium hydroxide / methanol

With pyridine; potassium hydroxide; In methanol;

Reference yield: 90.0%

: 67-56-1
methanol

: 17046-60-5
17β-estradiol-3,17-disulfate potassium salt

: 50-28-2
estradiol

Guidance literature:: With toluene-4-sulfonic acid; In 1,4-dioxane; water; at 60 ℃; for 72h; Further Variations:; Solvents; Temperatures; Product distribution;
DOI:10.1016/S0040-4039(00)01190-4