S-(2-amino-4-trifluoromethylphenyl)-N-benzyloxycarbonyl-L-cysteine hydrochloride

Base Information

Chemical Name:S-(2-amino-4-trifluoromethylphenyl)-N-benzyloxycarbonyl-L-cysteine hydrochloride
CAS No.:100236-30-4
Molecular Formula:C₁₈H₁₇F₃N₂O₄S*ClH
Molecular Weight:450.866
Hs Code.:

Synonyms:S-(2-amino-4-trifluoromethylphenyl)-N-benzyloxycarbonyl-L-cysteine hydrochloride

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Chemical Property of S-(2-amino-4-trifluoromethylphenyl)-N-benzyloxycarbonyl-L-cysteine hydrochloride

Chemical Property:

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Technology Process of S-(2-amino-4-trifluoromethylphenyl)-N-benzyloxycarbonyl-L-cysteine hydrochloride

There total 5 articles about S-(2-amino-4-trifluoromethylphenyl)-N-benzyloxycarbonyl-L-cysteine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: hydrogen chloride-ethyl acetate

: 98413-35-5
(R)-2-benzyloxycarbonylamino-3-(2-nitro-4-trifluoromethylphenyl)thiopropionic acid

: 100236-30-4
S-(2-amino-4-trifluoromethylphenyl)-N-benzyloxycarbonyl-L-cysteine hydrochloride

Guidance literature:: With acetic acid; In diethyl ether; water; ethyl acetate;

Reference yield:

: 98413-35-5
(R)-2-benzyloxycarbonylamino-3-(2-nitro-4-trifluoromethylphenyl)thiopropionic acid

: 100236-30-4
S-(2-amino-4-trifluoromethylphenyl)-N-benzyloxycarbonyl-L-cysteine hydrochloride

Guidance literature:: With hydrogenchloride; zinc; In water; acetic acid; for 0.833333h;
DOI:10.1248/cpb.34.1128

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 100236-30-4
S-(2-amino-4-trifluoromethylphenyl)-N-benzyloxycarbonyl-L-cysteine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / 2.5 N NaOH, HCl / H₂O / 3 h / 0 °C

2: 3.4 g / Zn, HCl / acetic acid; H₂O / 0.83 h

With hydrogenchloride; sodium hydroxide; zinc; In water; acetic acid;
DOI:10.1248/cpb.34.1128