(R)-2-benzyloxycarbonylamino-3-(2-nitro-4-trifluoromethylphenyl)thiopropionic acid

Base Information

Chemical Name:(R)-2-benzyloxycarbonylamino-3-(2-nitro-4-trifluoromethylphenyl)thiopropionic acid
CAS No.:98413-35-5
Molecular Formula:C₁₈H₁₅F₃N₂O₆S
Molecular Weight:444.388
Hs Code.:

Synonyms:(R)-2-benzyloxycarbonylamino-3-(2-nitro-4-trifluoromethylphenyl)thiopropionic acid

Suppliers and Price of (R)-2-benzyloxycarbonylamino-3-(2-nitro-4-trifluoromethylphenyl)thiopropionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of (R)-2-benzyloxycarbonylamino-3-(2-nitro-4-trifluoromethylphenyl)thiopropionic acid

Chemical Property:

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Technology Process of (R)-2-benzyloxycarbonylamino-3-(2-nitro-4-trifluoromethylphenyl)thiopropionic acid

There total 2 articles about (R)-2-benzyloxycarbonylamino-3-(2-nitro-4-trifluoromethylphenyl)thiopropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 501-53-1,94274-21-2
benzyl chloroformate

: 98413-16-2
(R)-2-Amino-3-(2-nitro-4-trifluoromethyl-phenylsulfanyl)-propionic acid

: 98413-35-5
(R)-2-benzyloxycarbonylamino-3-(2-nitro-4-trifluoromethylphenyl)thiopropionic acid

Guidance literature:: With hydrogenchloride; sodium hydroxide; In water; at 0 ℃; for 3h;
DOI:10.1248/cpb.34.1128

Reference yield:

: 400-98-6
4-trifluoromethyl-2-nitroaniline

: 98413-35-5
(R)-2-benzyloxycarbonylamino-3-(2-nitro-4-trifluoromethylphenyl)thiopropionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 41 percent / NaNO₂ / Ambient temperature

2: 72 percent / 2.5 N NaOH, HCl / H₂O / 3 h / 0 °C

With hydrogenchloride; sodium hydroxide; sodium nitrite; In water;
DOI:10.1248/cpb.34.1128