biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-methylesterpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester

Base Information

• Chemical Name: biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-methylesterpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester
• CAS No.: 864751-37-1
• Molecular Formula: C₃₆H₄₄N₄O₅
• Molecular Weight: 612.769
• Mol file: 864751-37-1.mol

Synonyms:biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-methylesterpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester

Chemical Property of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-methylesterpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-methylesterpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester

There total 1 articles about biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-methylesterpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

isonipecotic acid methyl ester (2971-79-1) + biphenyl-2-yl-carbamic acid 1-{2-[(4-formylbenzoyl)methylamino]ethyl}piperidin-4-yl ester → biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-methylesterpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester (864751-37-1)

Guidance literature:

isonipecotic acid methyl ester; biphenyl-2-yl-carbamic acid 1-{2-[(4-formylbenzoyl)methylamino]ethyl}piperidin-4-yl ester; With acetic acid; sodium sulfate; In isopropyl alcohol; at 0 - 20 ℃; for 1h;

With sodium tris(acetoxy)borohydride; In isopropyl alcohol; at 0 - 20 ℃; for 16h;

With hydrogenchloride; In dichloromethane; isopropyl alcohol;

Reference yield:

biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-methylesterpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester (864751-37-1) + methylamine (74-89-5) → biphenyl-2-ylcarbamic acid 1-(2-{methyl-[4-(4-methylcarbamoylpiperidin-1-ylmethyl)benzoyl]amino}ethyl)piperidin-4-yl ester

Guidance literature:

In methanol; at 60 ℃; for 72h;

upstream raw materials:

isonipecotic acid methyl ester