3-Bromo-3',5'-dichlorobenzophenone

Base Information

• Chemical Name: 3-Bromo-3',5'-dichlorobenzophenone
• CAS No.: 844879-42-1
• Molecular Formula: C₁₃H₇BrCl₂O
• Molecular Weight: 330.008
• DSSTox Substance ID: DTXSID20373622
• Wikidata: Q82161872
• Mol file: 844879-42-1.mol

Synonyms:3-Bromo-3',5'-dichlorobenzophenone;844879-42-1;(3-bromophenyl)-(3,5-dichlorophenyl)methanone;(3-bromophenyl)(3,5-dichlorophenyl)methanone;DTXSID20373622;MFCD06201468;AKOS016018480;CS-0362922;A864123;(3-Bromo-phenyl)-(3,5-dichloro-phenyl)-methanone

Chemical Property of 3-Bromo-3',5'-dichlorobenzophenone

Chemical Property:

• Vapor Pressure: 1.15E-07mmHg at 25°C
• Boiling Point: 432.0±45.0 °C(Predicted)
• Density: 1.589±0.06 g/cm3(Predicted)
• XLogP3: 5.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 327.90573
• Heavy Atom Count: 17
• Complexity: 275

Purity/Quality:

98%min ^*data from raw suppliers

3-Bromo-3',5'-dichlorobenzophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)Br)C(=O)C2=CC(=CC(=C2)Cl)Cl

Technology Process of 3-Bromo-3',5'-dichlorobenzophenone

There total 1 articles about 3-Bromo-3',5'-dichlorobenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

1,3-dibromobenzene (108-36-1) + 3,5-dichloro-N-methoxy-N-methylbenzamide (259796-12-8) → (3-bromophenyl)-(3,5-dichlorophenyl)methanone (844879-42-1)

Guidance literature:

1,3-dibromobenzene; With iodine; magnesium; In diethyl ether; at 20 - 30 ℃; Inert atmosphere;

3,5-dichloro-N-methoxy-N-methylbenzamide; In diethyl ether; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.bmcl.2009.12.090

Reference yield:

(3-bromophenyl)-(3,5-dichlorophenyl)methanone (844879-42-1) + thiosemicarbazide (79-19-6) → [(3-bromophenyl)-(3,5-dichlorophenyl)ketone]thiosemicarbazone + [(3-bromophenyl)-(3,5-dichlorophenyl)ketone]thiosemicarbazone

Guidance literature:

With toluene-4-sulfonic acid; In methanol; Inert atmosphere; Reflux;

DOI:10.1016/j.bmcl.2009.12.090

upstream raw materials:

1,3-dibromobenzene

3,5-dichloro-N-methoxy-N-methylbenzamide

Refernces