Technology Process of 1-(3-ethyl-4-nitrophenyl)cyclopropanecarbonitrile
There total 3 articles about 1-(3-ethyl-4-nitrophenyl)cyclopropanecarbonitrile which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tetrabutylammomium bromide; sodium hydroxide;
In
water; acetonitrile;
at 40 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: zinc(II) fluoride; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium(0) / N,N-dimethyl-formamide / 5 h / 150 °C / Inert atmosphere; Microwave irradiation
2: tetrabutylammomium bromide; sodium hydroxide / water; acetonitrile / 2 h / 40 °C
With
tris-(dibenzylideneacetone)dipalladium(0); zinc(II) fluoride; tetrabutylammomium bromide; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium hydroxide;
In
water; N,N-dimethyl-formamide; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: dihydrogen peroxide; trifluoroacetic anhydride / dichloromethane / 0 °C / Reflux
2: zinc(II) fluoride; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium(0) / N,N-dimethyl-formamide / 5 h / 150 °C / Inert atmosphere; Microwave irradiation
3: tetrabutylammomium bromide; sodium hydroxide / water; acetonitrile / 2 h / 40 °C
With
tris-(dibenzylideneacetone)dipalladium(0); zinc(II) fluoride; tetrabutylammomium bromide; dihydrogen peroxide; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; trifluoroacetic anhydride; sodium hydroxide;
In
dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
