3-Cyclohexyl-N-[(dimethylamino)sulfonyl]-1H-indole-6-carboxamide

Base Information

Chemical Name:3-Cyclohexyl-N-[(dimethylamino)sulfonyl]-1H-indole-6-carboxamide
CAS No.:1251033-29-0
Molecular Formula:C₁₇H₂₃N₃O₃S
Molecular Weight:349.454
Hs Code.:
Mol file:1251033-29-0.mol

Synonyms:3-cyclohexyl-N-(N,N-dimethylsulfamoyl)-1H-indole-6-carboxamide

Suppliers and Price of 3-Cyclohexyl-N-[(dimethylamino)sulfonyl]-1H-indole-6-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 9 raw suppliers

Chemical Property of 3-Cyclohexyl-N-[(dimethylamino)sulfonyl]-1H-indole-6-carboxamide

Chemical Property:

Density:1.302

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-Cyclohexyl-N-[(dimethylamino)sulfonyl]-1H-indole-6-carboxamide

There total 9 articles about 3-Cyclohexyl-N-[(dimethylamino)sulfonyl]-1H-indole-6-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1542138-96-4
N-(N,N-dimethylsulfamoyl)-1H-indole-6-carboxamide

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 1251033-29-0
3-cyclohexyl-N-(N,N-dimethylsulfamoyl)-1H-indole-6-carboxamide

Guidance literature:: N-(N,N-dimethylsulfamoyl)-1H-indole-6-carboxamide; cyclohexanone; With triethylsilane; In toluene; at 18 - 22 ℃; for 0.5h;

With trifluoroacetic acid; In toluene; at 45 ℃; Solvent; Temperature;

Reference yield:

: 3984-14-3
N,N-dimethylsulfamide

: 1092574-94-1
6-bromo-3-cyclohexyl-1H-indole

: 201230-82-2
carbon monoxide

: 1251033-29-0
3-cyclohexyl-N-(N,N-dimethylsulfamoyl)-1H-indole-6-carboxamide

Guidance literature:: N,N-dimethylsulfamide; 6-bromo-3-cyclohexyl-1H-indole; With (bis(2-(diphenylphosphino)phenyl)methane); palladium diacetate;

carbon monoxide; With potassium carbonate; In toluene; at 80 ℃; for 20h; under 2068.65 Torr;

Reference yield:

: C₂₂H₃₁N₃O₅S

: 1251033-29-0
3-cyclohexyl-N-(N,N-dimethylsulfamoyl)-1H-indole-6-carboxamide

Guidance literature:: C₂₂H₃₁N₃O₅S; With sodium hydroxide; In water; isopropyl alcohol; at 65 ℃; for 1h; Inert atmosphere; Large scale;

With hydrogenchloride; In water; isopropyl alcohol; Inert atmosphere; Large scale;
DOI:10.1021/acs.oprd.8b00214