4-Benzylpiperazin-2-one

Base Information

Chemical Name:4-Benzylpiperazin-2-one
CAS No.:13754-41-1
Molecular Formula:C11H14N2O
Molecular Weight:190.245
Hs Code.:2933599090
European Community (EC) Number:625-741-2
DSSTox Substance ID:DTXSID00466485
Nikkaji Number:J1.672.702D
Wikidata:Q72441703
Mol file:13754-41-1.mol

Synonyms:4-benzylpiperazin-2-one;13754-41-1;1-Benzyl-3-oxopiperazine;2-Piperazinone, 4-(phenylmethyl)-;MFCD06795962;Piperazinone, 4-(phenylmethyl)-;4-Benzyl-piperazin-2-one;2-Piperazinone,4-(phenylmethyl)-;4-(phenylmethyl)piperazinone;SCHEMBL220097;DTXSID00466485;1-Benzyl-3-oxopiperazine, 95%;SBWVHKNCFZRBRJ-UHFFFAOYSA-N;BCP23337;AKOS005287411;CS-W015882;SB12579;AS-11196;SY109984;AM20020451;FT-0647988;EN300-53593;A26392;AB01000543-01;J-007035;Z46334767

Suppliers and Price of 4-Benzylpiperazin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Benzylpiperazin-2-one
100mg
$ 60.00

Sigma-Aldrich
1-Benzyl-3-oxopiperazine 95%
1g
$ 84.60

Sigma-Aldrich
1-Benzyl-3-oxopiperazine 95%
5g
$ 296.00

Labseeker
1-BENZYL-3-OXOPIPERAZINE 95
250g
$ 1166.00

Labseeker
1-BENZYL-3-OXOPIPERAZINE 95
100g
$ 916.00

Crysdot
4-Benzylpiperazin-2-one 97%
25g
$ 523.00

Chemenu
4-Benzylpiperazin-2-one 95+%
25g
$ 489.00

Biosynth Carbosynth
4-Benzyl-piperazin-2-one
5 g
$ 297.50

Biosynth Carbosynth
4-Benzyl-piperazin-2-one
500 mg
$ 75.00

Biosynth Carbosynth
4-Benzyl-piperazin-2-one
2 g
$ 186.00

Total 38 raw suppliers

Chemical Property of 4-Benzylpiperazin-2-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:148-155 °C
Refractive Index:1.563
Boiling Point:366.617 °C at 760 mmHg
PKA:15.11±0.20(Predicted)
Flash Point:175.524 °C
PSA：32.34000
Density:1.13 g/cm³
LogP:0.88510
Storage Temp.:2-8°C
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:190.110613074
Heavy Atom Count:14
Complexity:200

Purity/Quality:

97% ^*data from raw suppliers

4-Benzylpiperazin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-36/37/38
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CC(=O)N1)CC2=CC=CC=C2
Uses Used in a copper-catalyzed amidation of an aryl bromide.

Technology Process of 4-Benzylpiperazin-2-one

There total 8 articles about 4-Benzylpiperazin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1430739-37-9
Boc-protected (α)N-benzyl-aeg methyl ester

: 13754-41-1
4-benzyl-piperazin-2-one

Guidance literature:: Boc-protected (α)N-benzyl-aeg methyl ester; With chlorotriisopropylsilane; trifluoroacetic acid; In dichloromethane; for 1h; Cooling with ice;

at 110 ℃; Inert atmosphere;
DOI:10.1002/cplu.201300343