trans-2-Amino-2,3-dihydro-1H-inden-1-ol

Base Information

Chemical Name:trans-2-Amino-2,3-dihydro-1H-inden-1-ol
CAS No.:13575-72-9
Molecular Formula:C9H11 N O
Molecular Weight:149.192
Hs Code.:2922199090
European Community (EC) Number:819-277-1
Nikkaji Number:J36.233F
Mol file:13575-72-9.mol

Synonyms:(1R,2R)-2-Amino-2,3-dihydro-1H-inden-1-ol;trans-2-Amino-2,3-dihydro-1H-inden-1-ol;94077-01-7;2alpha-Aminoindan-1beta-ol;SCHEMBL1240196;1H-Inden-1-ol, 2-amino-2,3-dihydro-, (1R,2R)-rel-;HRWCWYGWEVVDLT-RKDXNWHRSA-N;(+/-)-trans-2-Aminoindan-1-ol;EN300-399396;rac-(1R,2R)-2-amino-2,3-dihydro-1H-inden-1-ol

Suppliers and Price of trans-2-Amino-2,3-dihydro-1H-inden-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Aminoindan-1-ol
25mg
$ 105.00

TRC
2-Aminoindan-1-ol
250mg
$ 470.00

Matrix Scientific
2-Aminoindan-1-ol 97%
1g
$ 524.00

Crysdot
trans-2-Amino-2,3-dihydro-1H-inden-1-ol 95+%
1g
$ 493.00

Atlantic Research Chemicals
2-Aminoindan-1-ol 95%
1gm:
$ 307.51

Atlantic Research Chemicals
2-Aminoindan-1-ol 95%
250mgs:
$ 176.73

American Custom Chemicals Corporation
2-AMINOINDAN-1-OL 95.00%
5G
$ 1928.08

American Custom Chemicals Corporation
2-AMINOINDAN-1-OL 95.00%
2.5G
$ 1473.14

American Custom Chemicals Corporation
2-AMINOINDAN-1-OL 95.00%
1G
$ 983.52

AK Scientific
2-Aminoindan-1-ol
1g
$ 722.00

Total 9 raw suppliers

Chemical Property of trans-2-Amino-2,3-dihydro-1H-inden-1-ol

Chemical Property:

Vapor Pressure:0.000626mmHg at 25°C
Melting Point:105-106 °C
Refractive Index:1.626
Boiling Point:296.9°Cat760mmHg
PKA:13.85±0.40(Predicted)
Flash Point:133.4°C
PSA：46.25000
Density:1.212g/cm³
LogP:1.30370
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:149.084063974
Heavy Atom Count:11
Complexity:149

Purity/Quality:

99.99%HPLC ^*data from raw suppliers

2-Aminoindan-1-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(C2=CC=CC=C21)O)N
Isomeric SMILES:C1[C@H]([C@@H](C2=CC=CC=C21)O)N
General Description 2-Aminoindan-1-ol, also known as trans-2-aminoindan-1-ol, is a conformationally restricted substrate analog that undergoes stereospecific hydroxylation by dopamine β-hydroxylase (DBH) to yield predominantly the (1S,2S)-trans-2-amino-1-indanol (4S) with high enantiomeric excess (93% ee). This reaction involves pro-S hydrogen abstraction and oxygen binding with overall retention of configuration, distinguishing it from the pro-R hydroxylation observed in phenethylamine substrates. The findings suggest a specific interaction model between DBH and its substrates, highlighting the enzyme's stereochemical preference.

Technology Process of trans-2-Amino-2,3-dihydro-1H-inden-1-ol

There total 31 articles about trans-2-Amino-2,3-dihydro-1H-inden-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%