PYRIDIN-2-YL-UREA

Base Information

• Chemical Name: PYRIDIN-2-YL-UREA
• CAS No.: 13114-64-2
• Molecular Formula: C6H7 N3 O
• Molecular Weight: 137.141
• Hs Code.: 2933399090
• Mol file: 13114-64-2.mol

Synonyms:Urea,(2-pyridyl)- (6CI,7CI,8CI); Urea, 2-pyridinyl- (9CI); 1-(2-Pyridyl)urea;2-Pyridylcarbamide

Chemical Property of PYRIDIN-2-YL-UREA

Chemical Property:

• Vapor Pressure: 0.00655mmHg at 25°C
• Melting Point: 173 °C
• Refractive Index: 1.649
• Boiling Point: 271.2°Cat760mmHg
• Flash Point: 117.8°C
• PSA: 68.01000
• Density: 1.332g/cm³
• LogP: 1.34550

Purity/Quality:

97% ^*data from raw suppliers

Pyridin-2-yl-urea ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,Xn
• Statements: 22-36/37/38
• Safety Statements: 26

MSDS Files:

Useful:

Technology Process of PYRIDIN-2-YL-UREA

There total 4 articles about PYRIDIN-2-YL-UREA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-aminopyridine (504-29-0) + urea (57-13-6) → N-(Pyridin-2-yl)urea (13114-64-2)

Guidance literature:

In neat (no solvent); at 149.9 ℃; for 5h;

DOI:10.1107/S0108270197004782

Reference yield: 62.0%

2-aminopyridine (504-29-0) + isocyanate de chlorosulfonyle (1189-71-5) → N-(Pyridin-2-yl)urea (13114-64-2)

Guidance literature:

In acetonitrile; at 0 - 20 ℃; for 3.33h;

DOI:10.1039/b105420c

Reference yield:

2-aminopyridine (504-29-0) + urea (57-13-6) → N-(Pyridin-2-yl)urea (13114-64-2)

Guidance literature:

upstream raw materials:

2-aminopyridine

urea

isocyanate de chlorosulfonyle

Downstream raw materials:

ethyl 2-pyridinylcarbamate

1,3-di-pyridin-2-yl-urea

3-(4-cyanophenyl)-1-(pyridin-2-yl)urea