3-phenyl-1-(trimethylsilyl)propyl diisopropylcarbamate

Base Information

• Chemical Name: 3-phenyl-1-(trimethylsilyl)propyl diisopropylcarbamate
• CAS No.: 1270304-91-0
• Molecular Formula: C₁₉H₃₃NO₂Si
• Molecular Weight: 335.562
• Mol file: 1270304-91-0.mol

Synonyms:3-phenyl-1-(trimethylsilyl)propyl diisopropylcarbamate

Chemical Property of 3-phenyl-1-(trimethylsilyl)propyl diisopropylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 3-phenyl-1-(trimethylsilyl)propyl diisopropylcarbamate

There total 1 articles about 3-phenyl-1-(trimethylsilyl)propyl diisopropylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloro-trimethyl-silane (75-77-4) + 3-phenylpropyl N,N-diisopropylcarbamate (218601-55-9) → 3-phenyl-1-(trimethylsilyl)propyl diisopropylcarbamate (1270304-91-0)

Guidance literature:

3-phenylpropyl N,N-diisopropylcarbamate; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In diethyl ether; cyclohexane; at -78 ℃; for 5h; Inert atmosphere;

chloro-trimethyl-silane; In diethyl ether; cyclohexane; at 23 ℃; Inert atmosphere;

DOI:10.1021/ol200177f

Reference yield: 88.0%

3-phenyl-1-(trimethylsilyl)propyl diisopropylcarbamate (1270304-91-0) + 2,4,4,5,5-pentamethyl-[1,3,2]dioxaborolane (94242-85-0) → trimethyl[(1S)-1-methyl-3-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propyl]silane (1270304-83-0)

Guidance literature:

3-phenyl-1-(trimethylsilyl)propyl diisopropylcarbamate; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In diethyl ether; cyclohexane; at -78 ℃; for 5h; Inert atmosphere;

2,4,4,5,5-pentamethyl-[1,3,2]dioxaborolane; In diethyl ether; cyclohexane; at -78 ℃; Inert atmosphere; Reflux;

DOI:10.1021/ol200177f

upstream raw materials:

chloro-trimethyl-silane

3-phenylpropyl N,N-diisopropylcarbamate

Downstream raw materials:

trimethyl[(1S)-1-methyl-3-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propyl]silane