C₈H₄ClFN₂

Base Information

Chemical Name:C₈H₄ClFN₂
CAS No.:1378470-92-8
Molecular Formula:C₈H₄ClFN₂
Molecular Weight:182.585
Hs Code.:2933998090

C<sub>8</sub>H<sub>4</sub>ClFN<sub>2</sub>

Synonyms:C₈H₄ClFN₂

Suppliers and Price of C₈H₄ClFN₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-Chloro-7-fluoro-1,5-naphthyridine 97%
250 mg
$ 370.00

Crysdot
2-Chloro-7-fluoro-1,5-naphthyridine 97%
1g
$ 751.00

Crysdot
2-Chloro-7-fluoro-1,5-naphthyridine 97%
5g
$ 2257.00

Apolloscientific
2-Chloro-7-fluoro-1,5-naphthyridine >97%
250mg
$ 231.00

Alichem
2-Chloro-7-fluoro-1,5-naphthyridine
5g
$ 2658.45

Alichem
2-Chloro-7-fluoro-1,5-naphthyridine
1g
$ 821.94

Total 3 raw suppliers

Chemical Property of C₈H₄ClFN₂

Chemical Property:

Boiling Point:285.4±35.0 °C(Predicted)
Density:1.447±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-7-fluoro-1,5-naphthyridine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₈H₄ClFN₂

There total 5 articles about C₈H₄ClFN₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 959615-64-6
7-fluoro-1,5-naphthyridin-2(1H)-one

: 1378470-92-8
C₈H₄ClFN₂

Guidance literature:: With trichlorophosphate; In N,N-dimethyl-formamide; toluene; at 110 ℃;
DOI:10.1021/op500100b

Reference yield:

: 82671-06-5
2,6-dichloro-5-fluoro-3-pyridinecarboxylic acid

: 1378470-92-8
C₈H₄ClFN₂

Guidance literature:: Multi-step reaction with 5 steps

1: palladium diacetate; triphenylphosphine; formic acid / 70 °C

2: triethylamine; diphenyl phosphoryl azide; tert-butyl alcohol / 80 °C

3: palladium diacetate; triphenylphosphine; sodium carbonate / acetic acid butyl ester / 130 °C

4: acetic acid; tributylphosphine / 110 °C

5: trichlorophosphate / N,N-dimethyl-formamide; toluene / 110 °C

With formic acid; tributylphosphine; diphenyl phosphoryl azide; palladium diacetate; sodium carbonate; acetic acid; triethylamine; triphenylphosphine; tert-butyl alcohol; trichlorophosphate; In acetic acid butyl ester; N,N-dimethyl-formamide; toluene; 2: |Curtius Rearrangement / 2: |Curtius Rearrangement / 3: |Heck Reaction;
DOI:10.1021/op500100b

Reference yield:

: 38186-88-8
2-chloro-5-fluoronicotinic acid

: 1378470-92-8
C₈H₄ClFN₂

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine; diphenyl phosphoryl azide; tert-butyl alcohol / 80 °C

2: palladium diacetate; triphenylphosphine; sodium carbonate / acetic acid butyl ester / 130 °C

3: acetic acid; tributylphosphine / 110 °C

4: trichlorophosphate / N,N-dimethyl-formamide; toluene / 110 °C

With tributylphosphine; diphenyl phosphoryl azide; palladium diacetate; sodium carbonate; acetic acid; triethylamine; triphenylphosphine; tert-butyl alcohol; trichlorophosphate; In acetic acid butyl ester; N,N-dimethyl-formamide; toluene; 1: |Curtius Rearrangement / 1: |Curtius Rearrangement / 2: |Heck Reaction;
DOI:10.1021/op500100b