(2R,3S,4R)-1,3-isopropylidenedioxy-2,4-dimethyl-5-(phenylsulfonyl)pentane

Base Information

Chemical Name:(2R,3S,4R)-1,3-isopropylidenedioxy-2,4-dimethyl-5-(phenylsulfonyl)pentane
CAS No.:194291-43-5
Molecular Formula:C₁₆H₂₄O₄S
Molecular Weight:312.43
Hs Code.:

Synonyms:(2R,3S,4R)-1,3-isopropylidenedioxy-2,4-dimethyl-5-(phenylsulfonyl)pentane

Suppliers and Price of (2R,3S,4R)-1,3-isopropylidenedioxy-2,4-dimethyl-5-(phenylsulfonyl)pentane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (2R,3S,4R)-1,3-isopropylidenedioxy-2,4-dimethyl-5-(phenylsulfonyl)pentane

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3S,4R)-1,3-isopropylidenedioxy-2,4-dimethyl-5-(phenylsulfonyl)pentane

There total 7 articles about (2R,3S,4R)-1,3-isopropylidenedioxy-2,4-dimethyl-5-(phenylsulfonyl)pentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 77-76-9
2,2-dimethoxy-propane

: 194291-47-9
(2R,3S,4R)-2,4-dimethyl-5-(phenylsulfonyl)pentane-1,3-diol

: 194291-43-5
(2R,3S,4R)-1,3-isopropylidenedioxy-2,4-dimethyl-5-(phenylsulfonyl)pentane

Guidance literature:: With (1S)-10-camphorsulfonic acid; In benzene;
DOI:10.1016/S0040-4039(97)01118-0

Reference yield:

: 180188-59-4
(2S,3R,4R)-5-acetoxy-3-benzyloxy-2,4-dimethylpentanol

: 194291-43-5
(2R,3S,4R)-1,3-isopropylidenedioxy-2,4-dimethyl-5-(phenylsulfonyl)pentane

Guidance literature:: Multi-step reaction with 5 steps

1: 95 percent / pyridine; tri-n-butylphosphine / 30 h / 20 °C

2: 96 percent / MCPBA / CH₂Cl₂ / 24 h / 0 - 20 °C

3: 100 percent / K₂CO₃ / methanol / 0.5 h / 20 °C

4: 95 percent / hydrogen / Pd(OH)2-C / methanol / 2 h / 20 °C

5: 87 percent / 10-camphorsulfonic acid / benzene / 24 h / 20 °C

With pyridine; tributylphosphine; (1S)-10-camphorsulfonic acid; hydrogen; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; palladium hydroxide - carbon; In methanol; dichloromethane; benzene;
DOI:10.1016/j.tet.2005.10.013

Reference yield:

: 194291-44-6
(2R,3S,4R)-3-benzyloxy-2,4-dimethyl-5-(phenylthio)pentyl acetate

: 194291-43-5
(2R,3S,4R)-1,3-isopropylidenedioxy-2,4-dimethyl-5-(phenylsulfonyl)pentane

Guidance literature:: Multi-step reaction with 4 steps

1: 96 percent / MCPBA / CH₂Cl₂ / 24 h / 0 - 20 °C

2: 100 percent / K₂CO₃ / methanol / 0.5 h / 20 °C

3: 95 percent / hydrogen / Pd(OH)2-C / methanol / 2 h / 20 °C

4: 87 percent / 10-camphorsulfonic acid / benzene / 24 h / 20 °C

With (1S)-10-camphorsulfonic acid; hydrogen; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; palladium hydroxide - carbon; In methanol; dichloromethane; benzene;
DOI:10.1016/j.tet.2005.10.013