180188-59-4

Upstream product

• 108-05-4 vinyl acetate 
• 100-39-0 benzyl bromide 
• 95671-21-9 2,4-dimethyl-2,4-dideoxy-xylitol 

Downstream Products

• 194291-47-9 (2R,3S,4R)-2,4-dimethyl-5-(phenylsulfonyl)pentane-1,3-diol 
• 194291-43-5 (2R,3S,4R)-1,3-isopropylidenedioxy-2,4-dimethyl-5-(phenylsulfonyl)pentane 
• 194291-48-0 (5R,6S,7R)-6,8-isopropylidenedioxy-5,7-dimethyl-4-phenylsulfonyl-1-octene 
• 194291-46-8 (2R,3S,4R)-3-benzyloxy-2,4-dimethyl-5-phenylsulfonyl-1-pentanol 
• 194291-45-7 (2R,3S,4R)-3-benzyloxy-2,4-dimethyl-5-(phenylsulfonyl)pentyl acetate 
• 875631-03-1 (2S,8S)-3-Benzenesulfonyl-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-8-((4R,5R)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-nonan-5-ol 

Relevant academic research and scientific papers

Enzymatic hydrolysis of meso(syn-syn)-1,3,5-triacetoxy-2,4- dimethylpentane and acetylation of meso(syn-syn)-3-benzyloxy-2,4- dimethylpentane-1,5-diol by lipase

Chiral inductions of meso triacetate (4) and meso diol (15) were carried out on the basis of enzymatic reaction using lipase to give chiral synthons having three consecutive chiral centers with high enantiomeric excess.

Synthetic study of tautomycin. I. Synthesis and regioselective enzymatic acetylationof a spiroketal diol related to the C5-C16 fragment

Spiroketal diol 1 was prepared from 5, which can be obtained by enantio-selective enzymatic acetylation of meso diol 6, in 12 steps in 16.5% total yield and its regioselective protection was achieved by an enzymatic method to give 1 6 in high yield.