syn-(2R,3R,11R,12R)-(+)-2,11-bis(4',4'-dimethyl-2-oxazoline-2-yl)-3,12-dicarboxanilide-1,4,7,10,13,16-hexaoxacyclooctadecane

Base Information

Chemical Name:syn-(2R,3R,11R,12R)-(+)-2,11-bis(4',4'-dimethyl-2-oxazoline-2-yl)-3,12-dicarboxanilide-1,4,7,10,13,16-hexaoxacyclooctadecane
CAS No.:111216-19-4
Molecular Formula:C₃₆H₄₈N₄O₁₀
Molecular Weight:696.798
Hs Code.:

Synonyms:syn-(2R,3R,11R,12R)-(+)-2,11-bis(4',4'-dimethyl-2-oxazoline-2-yl)-3,12-dicarboxanilide-1,4,7,10,13,16-hexaoxacyclooctadecane

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Chemical Property of syn-(2R,3R,11R,12R)-(+)-2,11-bis(4',4'-dimethyl-2-oxazoline-2-yl)-3,12-dicarboxanilide-1,4,7,10,13,16-hexaoxacyclooctadecane

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Technology Process of syn-(2R,3R,11R,12R)-(+)-2,11-bis(4',4'-dimethyl-2-oxazoline-2-yl)-3,12-dicarboxanilide-1,4,7,10,13,16-hexaoxacyclooctadecane

There total 2 articles about syn-(2R,3R,11R,12R)-(+)-2,11-bis(4',4'-dimethyl-2-oxazoline-2-yl)-3,12-dicarboxanilide-1,4,7,10,13,16-hexaoxacyclooctadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 97462-83-4
(2R,3R,11R,12R)-3,12-Bis-phenylcarbamoyl-1,4,7,10,13,16-hexaoxa-cyclooctadecane-2,11-dicarboxylic acid dimethyl ester

: 124-68-5
2-Amino-2-methyl-1-propanol

: 111216-19-4
syn-(2R,3R,11R,12R)-(+)-2,11-bis(4',4'-dimethyl-2-oxazoline-2-yl)-3,12-dicarboxanilide-1,4,7,10,13,16-hexaoxacyclooctadecane

Guidance literature:: With phosphorus pentoxide; In xylene; Heating;

Reference yield:

: 76798-13-5
(2R,3R,11R,12R)-3,12-Bis-phenylcarbamoyl-1,4,7,10,13,16-hexaoxa-cyclooctadecane-2,11-dicarboxylic acid

: 111216-19-4
syn-(2R,3R,11R,12R)-(+)-2,11-bis(4',4'-dimethyl-2-oxazoline-2-yl)-3,12-dicarboxanilide-1,4,7,10,13,16-hexaoxacyclooctadecane

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / tetrahydrofuran; diethyl ether / 0 °C

2: 86 percent / P₂O₅ / xylene / Heating

With phosphorus pentoxide; In tetrahydrofuran; diethyl ether; xylene;