2 3-DIMETHOXYNAPHTHALENE 97

Base Information

• Chemical Name: 2 3-DIMETHOXYNAPHTHALENE 97
• CAS No.: 10103-06-7
• Molecular Formula: C12H12 O2
• Molecular Weight: 188.226
• Hs Code.: 2909309090
• Mol file: 10103-06-7.mol

Synonyms:2,3-Dimethoxynaphthalene

Chemical Property of 2 3-DIMETHOXYNAPHTHALENE 97

Chemical Property:

• Vapor Pressure: 0.00262mmHg at 25°C
• Melting Point: 116.5-120.5 °C(lit.)
• Refractive Index: 1.584
• Boiling Point: 295.9°C at 760 mmHg
• Flash Point: 120.7°C
• PSA: 18.46000
• Density: 1.097g/cm³
• LogP: 2.85700
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

≥99% ^*data from raw suppliers

2,3-Dimethoxynaphthalene 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: It is used as a pharmaceutical intermediate.

Technology Process of 2 3-DIMETHOXYNAPHTHALENE 97

There total 38 articles about 2 3-DIMETHOXYNAPHTHALENE 97 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

dimethyl sulfate (77-78-1) + 2,3-naphthalenediol (92-44-4) → 2,3-dimethoxynaphthalene (10103-06-7)

Guidance literature:

With sodium hydroxide; triisooctyl amine; In dichloromethane; water; at 0 ℃; for 10h;

DOI:10.1039/b717797f

Reference yield: 95.0%

cis,trans-2,5-dimethoxytetrahydrofuran (696-59-3) + 1,2-dimethoxybenzene (91-16-7) → 2,3-dimethoxynaphthalene (10103-06-7)

Guidance literature:

With trifluorormethanesulfonic acid; In dichloromethane; at 0 - 20 ℃; for 2h; Reagent/catalyst; Inert atmosphere;

DOI:10.1021/ol501006t

Reference yield: 93.3%

carbonic acid dimethyl ester (616-38-6) + 2,3-naphthalenediol (92-44-4) → 2,3-dimethoxynaphthalene (10103-06-7)

Guidance literature:

With caesium carbonate; In acetonitrile; at 160 ℃; for 2h; under 0 - 8550.86 Torr; Microwave irradiation;

upstream raw materials:

N-(6,7-dimethoxy-1,2,3,4-tetrahydro-[1]naphthyl)-acetamide

6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydronaphthalene

dimethyl sulfate

2,3-naphthalenediol

Downstream raw materials:

1,2,3,4-tetramethoxynaphthalene

2,3-dimethoxy-1,4-naphthoquinone

1,3,4-Trimethoxy-naphthalen-2-ol

1,4,6,7-tetramethoxynaphthalene