C₂₅H₂₆F₃N₃O₂

Base Information

Chemical Name:C₂₅H₂₆F₃N₃O₂
CAS No.:1403946-37-1
Molecular Formula:C₂₅H₂₆F₃N₃O₂
Molecular Weight:457.496
Hs Code.:

C<sub>25</sub>H<sub>26</sub>F<sub>3</sub>N<sub>3</sub>O<sub>2</sub>

Synonyms:C₂₅H₂₆F₃N₃O₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₅H₂₆F₃N₃O₂

Chemical Property:

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Technology Process of C₂₅H₂₆F₃N₃O₂

There total 4 articles about C₂₅H₂₆F₃N₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 354574-25-7
C₁₈H₂₂N₂O₃

: 98-16-8
3-trifluoromethylaniline

: 1403946-37-1
C₂₅H₂₆F₃N₃O₂

Guidance literature:: C₁₈H₂₂N₂O₃; With methanesulfonyl chloride; triethylamine; In ISOPROPYLAMIDE; at 0 ℃; for 0.25h;

3-trifluoromethylaniline; With triethylamine; In ISOPROPYLAMIDE; at 0 ℃; for 0.833333h;

Reference yield:

: 3652-48-0
ethyl 2-methyl-5-phenyl-1H-pyrrole-3-carboxylate

: 1403946-37-1
C₂₅H₂₆F₃N₃O₂

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C

1.2: 4 h / 0 - 80 °C

2.1: sodium hydroxide; water / ethanol; tetrahydrofuran / 80 °C

3.1: triethylamine; methanesulfonyl chloride / ISOPROPYLAMIDE / 0.25 h / 0 °C

3.2: 0.83 h / 0 °C

With water; sodium hydride; methanesulfonyl chloride; triethylamine; sodium hydroxide; In tetrahydrofuran; ethanol; ISOPROPYLAMIDE; N,N-dimethyl-formamide;

Reference yield:

: 70-11-1
α-bromoacetophenone

: 1403946-37-1
C₂₅H₂₆F₃N₃O₂

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C / Inert atmosphere

1.2: 0.75 h / 0 - 20 °C

2.1: ammonium acetate; acetic acid / 4 h / 80 °C

3.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C

3.2: 4 h / 0 - 80 °C

4.1: sodium hydroxide; water / ethanol; tetrahydrofuran / 80 °C

5.1: triethylamine; methanesulfonyl chloride / ISOPROPYLAMIDE / 0.25 h / 0 °C

5.2: 0.83 h / 0 °C

With ammonium acetate; water; sodium hydride; acetic acid; methanesulfonyl chloride; triethylamine; sodium hydroxide; In tetrahydrofuran; ethanol; ISOPROPYLAMIDE; N,N-dimethyl-formamide;