benzyl 2-benzyloxy-3,5-di-tert-butylbenzoate

Base Information

• Chemical Name: benzyl 2-benzyloxy-3,5-di-tert-butylbenzoate
• CAS No.: 175650-08-5
• Molecular Formula: C₂₉H₃₄O₃
• Molecular Weight: 430.587
• Mol file: 175650-08-5.mol

Synonyms:benzyl 2-benzyloxy-3,5-di-tert-butylbenzoate

Chemical Property of benzyl 2-benzyloxy-3,5-di-tert-butylbenzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of benzyl 2-benzyloxy-3,5-di-tert-butylbenzoate

There total 1 articles about benzyl 2-benzyloxy-3,5-di-tert-butylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3,5-ditertbutyl salicylic acid (19715-19-6) + benzyl bromide (100-39-0) → benzyl 2-benzyloxy-3,5-di-tert-butylbenzoate (175650-08-5)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; for 2h; Ambient temperature;

DOI:10.1002/cber.19961290113

Reference yield: 88.0%

benzyl 2-benzyloxy-3,5-di-tert-butylbenzoate (175650-08-5) → 2-benzyloxy-3,5-di-tert-butylbenzoic acid (175650-09-6)

Guidance literature:

With potassium hydroxide; In methanol; at 40 ℃; for 48h;

DOI:10.1002/cber.19961290113

Reference yield:

benzyl 2-benzyloxy-3,5-di-tert-butylbenzoate (175650-08-5) → 2-benzyloxy-3,5-di-tert-butylbenzoyl chloride (175650-10-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / 50percent aq. KOH / methanol / 48 h / 40 °C

2: 79 percent / SOCl₂ / dimethylformamide / 40 - 45 °C

With potassium hydroxide; thionyl chloride; In methanol; N,N-dimethyl-formamide;

DOI:10.1002/cber.19961290113

upstream raw materials:

3,5-ditertbutyl salicylic acid

benzyl bromide

Downstream raw materials:

2-benzyloxy-3,5-di-tert-butylbenzoic acid

2-benzyloxy-3,5-di-tert-butylbenzoyl chloride

Refernces